Protein Info for ABIE53_003216 in Paraburkholderia graminis OAS925

Annotation: aminopeptidase N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 924 TIGR02414: aminopeptidase N" amino acids 37 to 923 (887 residues), 1227.7 bits, see alignment E=0 PF17900: Peptidase_M1_N" amino acids 118 to 213 (96 residues), 47.8 bits, see alignment E=3.8e-16 PF01433: Peptidase_M1" amino acids 253 to 476 (224 residues), 179.3 bits, see alignment E=1.7e-56 PF11940: DUF3458" amino acids 481 to 590 (110 residues), 91.4 bits, see alignment E=8.2e-30 PF17432: DUF3458_C" amino acids 594 to 924 (331 residues), 407.2 bits, see alignment E=1.2e-125

Best Hits

KEGG orthology group: K01256, aminopeptidase N [EC: 3.4.11.2] (inferred from 94% identity to bug:BC1001_2696)

Predicted SEED Role

"Membrane alanine aminopeptidase N (EC 3.4.11.2)" (EC 3.4.11.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.2

Use Curated BLAST to search for 3.4.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (924 amino acids)

>ABIE53_003216 aminopeptidase N (Paraburkholderia graminis OAS925)
MARQARLARLRAPAARVPSLQNAMADTATPNVIRRADYAPPAFLIDTVALEFDLLPERTV
VKNTMRVRRNPDAARAPHLELMGEQLEFVGATLDGQPFANAHPHEHGLVLDNVPDSFELT
LTSICNPAANTTLSGLYVSSGNFFTQCEAEGFRRITYFLDRPDVMSTYRVMLRASKADYP
VLLSNGNLLEEGDLPDGRHFARWEDPFRKPSYLFALVAGKLVALEERLKTGSGKEKLLQV
WVEPHDLDKTRHAMDSLINSIRWDEQRFGLELDLDRFMIVAVSDFNMGAMENKGLNIFNT
KYVLANPETATDTDFANIEAVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSAD
MAAGLTSSGDEAARATKRIEDVRVLRQMQFAEDAGPMAHPVRPESYVEINNFYTMTVYEK
GSEVVRMYQTLFGRDGFRKGMDLYFKRHDGQAVTCDDFRHALADANGRDLAQFERWYSQA
GTPRVSVRTRYDAAARRYSVTLTQGYGDAAPAARETQKGPLLIPFAIGLIGKDGNDLPLQ
LEGEARASDSTTRVLELTQTEQTFTFVNVEDEPLPSLLRNFSAPVIVEYDYPAEQLAFLL
AHDSDPFNRWEAGQRLATRELLTLAGQAANGAQLQLDDSVVAAFARVLTDESLSPAFREL
ALMLPSEAYLAEQMTESNPAAVHAARQFVRKRLANALKGEWLSIYEKHRTAGPYVATPAA
AGHRALKNLALSYLTELDDPAEAVRLASAQYEAANNMTDRAAALSALLNAAAANGGSAEA
QHALDDFYRRFEKEPLVIDKWFALQATQRGSAQRPVIEIVRKLMTHPAFNLKNPNRARSL
IFSFCAANPAQFHAQDGSGYAFWADQVIALDAINPQVAARLARSLELWRRFTPTLRDGMR
AALEKVASQVKSRDVREIVEKALA