Protein Info for ABIE53_003175 in Paraburkholderia graminis OAS925

Annotation: tetratricopeptide (TPR) repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 615 PF13432: TPR_16" amino acids 11 to 69 (59 residues), 30.2 bits, see alignment 5.2e-10 amino acids 73 to 137 (65 residues), 49.6 bits, see alignment E=4.4e-16 amino acids 120 to 170 (51 residues), 37.5 bits, see alignment 2.8e-12 amino acids 177 to 239 (63 residues), 41.2 bits, see alignment E=1.9e-13 amino acids 243 to 305 (63 residues), 34.4 bits, see alignment E=2.5e-11 amino acids 279 to 329 (51 residues), 23.9 bits, see alignment 4.8e-08 PF13181: TPR_8" amino acids 36 to 68 (33 residues), 15.7 bits, see alignment (E = 1.4e-05) amino acids 71 to 101 (31 residues), 20.9 bits, see alignment (E = 3e-07) amino acids 105 to 136 (32 residues), 19.1 bits, see alignment (E = 1.2e-06) amino acids 137 to 169 (33 residues), 24.8 bits, see alignment (E = 1.7e-08) amino acids 172 to 202 (31 residues), 17.7 bits, see alignment (E = 3.3e-06) amino acids 207 to 237 (31 residues), 20.4 bits, see alignment (E = 4.3e-07) amino acids 241 to 271 (31 residues), 20.9 bits, see alignment (E = 3e-07) amino acids 275 to 305 (31 residues), 13.2 bits, see alignment (E = 9.1e-05) PF13176: TPR_7" amino acids 37 to 68 (32 residues), 14 bits, see alignment (E = 4.7e-05) amino acids 105 to 136 (32 residues), 19.1 bits, see alignment (E = 1.1e-06) amino acids 140 to 168 (29 residues), 20.1 bits, see alignment (E = 5.4e-07) amino acids 207 to 237 (31 residues), 16.9 bits, see alignment (E = 5.4e-06) PF07721: TPR_4" amino acids 37 to 60 (24 residues), 12.4 bits, see alignment (E = 0.00022) amino acids 103 to 128 (26 residues), 20.7 bits, see alignment (E = 4.7e-07) amino acids 139 to 162 (24 residues), 15.8 bits, see alignment (E = 1.9e-05) amino acids 206 to 229 (24 residues), 11.3 bits, see alignment (E = 0.00052) amino acids 307 to 327 (21 residues), 11.1 bits, see alignment (E = 0.00059) PF14559: TPR_19" amino acids 47 to 89 (43 residues), 29.2 bits, see alignment 9.9e-10 amino acids 81 to 138 (58 residues), 31.8 bits, see alignment 1.5e-10 amino acids 183 to 237 (55 residues), 28.6 bits, see alignment 1.5e-09 amino acids 218 to 276 (59 residues), 29.3 bits, see alignment 9.3e-10 PF07719: TPR_2" amino acids 70 to 101 (32 residues), 24.1 bits, see alignment (E = 2.7e-08) amino acids 104 to 136 (33 residues), 30.8 bits, see alignment (E = 1.9e-10) amino acids 138 to 170 (33 residues), 27.9 bits, see alignment (E = 1.7e-09) amino acids 206 to 237 (32 residues), 24.3 bits, see alignment (E = 2.5e-08) PF13374: TPR_10" amino acids 70 to 98 (29 residues), 15.2 bits, see alignment (E = 1.9e-05) amino acids 138 to 167 (30 residues), 21.3 bits, see alignment (E = 2.2e-07) amino acids 171 to 199 (29 residues), 15.5 bits, see alignment (E = 1.5e-05) PF13428: TPR_14" amino acids 70 to 111 (42 residues), 24.2 bits, see alignment 3.8e-08 PF00515: TPR_1" amino acids 72 to 102 (31 residues), 28.4 bits, see alignment (E = 1.1e-09) amino acids 105 to 136 (32 residues), 32.7 bits, see alignment (E = 4.8e-11) amino acids 137 to 169 (33 residues), 33.5 bits, see alignment (E = 2.6e-11) PF13414: TPR_11" amino acids 76 to 117 (42 residues), 45.5 bits, see alignment 5e-15 amino acids 110 to 151 (42 residues), 36.5 bits, see alignment 3.3e-12 PF13174: TPR_6" amino acids 105 to 135 (31 residues), 13.3 bits, see alignment (E = 0.00012) PF13424: TPR_12" amino acids 105 to 167 (63 residues), 38.7 bits, see alignment E=9.8e-13 amino acids 137 to 199 (63 residues), 41.2 bits, see alignment E=1.7e-13 amino acids 171 to 235 (65 residues), 32.8 bits, see alignment E=7e-11 PF13431: TPR_17" amino acids 125 to 158 (34 residues), 26.1 bits, see alignment (E = 7.4e-09)

Best Hits

KEGG orthology group: None (inferred from 94% identity to bug:BC1001_2657)

Predicted SEED Role

"TPR repeat"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (615 amino acids)

>ABIE53_003175 tetratricopeptide (TPR) repeat protein (Paraburkholderia graminis OAS925)
MQPVFDRAFAAHRDGRLDDAERGYRATLDGNPAHVDALHLLGVLRHQQGQHAEAAELVRR
AVNLRPQDAALQLNLGNALKALGQIDEAIDQFRNALTLAPSFPMAHYNLGNAYAATGRHE
DAADAFRRSLHLQPDDASSHNNLGNALHALGRHEEAIASFRRTLELRPGHAGALNNMGMS
LNALGRADEAIPCFKAALAAEPRFVAAHFNLANTFDATGRHAQAVASFEAALALQPNLPP
AIYGMGNALAALGRHTEAIPYLERSVGLDPQFALAWLSLGTAHQALGAHATALRAFDQAL
RLQPDLASAHMNRALAWLALGDFARGLPEYEWRLQTVAEPAIETLPRWHGEPAAQRTLLI
HAEQGFGDTLQFVRFVSLAAQRAARVVLEVQPPLLPLLAPVAEAWRVTLIARGAPRPAAD
VQCPLLSLPLALGTTFATIPERTPYLSAPPAYRRKWRGSIGGQAKRKIGLAWSGRIQQNE
TRSMPLAALEPLFALEGIDWIVLQPHLSAEERAALDGHPRGGSIHRFDERIGDFADTAAI
IERLDAVVSIDTSIAHLAGALRKPLWLMLPFAPDWRWCHDDARSPWYASAKLVRQPRPGA
WREVVEAVAEELRRG