Protein Info for ABIE53_002999 in Paraburkholderia graminis OAS925

Annotation: ATP-dependent Zn protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 101 to 121 (21 residues), see Phobius details PF06480: FtsH_ext" amino acids 11 to 92 (82 residues), 45 bits, see alignment E=2.7e-15 TIGR01241: ATP-dependent metallopeptidase HflB" amino acids 105 to 396 (292 residues), 523.6 bits, see alignment E=2.7e-161 PF06068: TIP49" amino acids 158 to 223 (66 residues), 26 bits, see alignment E=1.3e-09 PF07728: AAA_5" amino acids 189 to 309 (121 residues), 24.2 bits, see alignment E=7.3e-09 PF00004: AAA" amino acids 190 to 322 (133 residues), 162.1 bits, see alignment E=2.3e-51 PF17862: AAA_lid_3" amino acids 345 to 389 (45 residues), 55.4 bits, see alignment 8.4e-19

Best Hits

Predicted SEED Role

"Cell division protein FtsH (EC 3.4.24.-)" in subsystem Bacterial Cell Division (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (465 amino acids)

>ABIE53_002999 ATP-dependent Zn protease (Paraburkholderia graminis OAS925)
MNNNMFSKAAVWLVIALVLFTVFKQFDKPRVQEGVSYSQFMDDAKNGKVKNVIVQGRNLT
VTPADGQKYQIVSPGDIWMVGDLMKYGVQVSGKADDEPNALVSALYYLGPTILIIGFWFY
MMRQMQGGGKGGAFSFGKSRARLIDENNNAINFTDVAGCDEAKEEVSELVDFLRDPQKFQ
KLGGRIPRGVLLVGPPGTGKTLLARAIAGEAKVPFFSISGSDFVEMFVGVGAARVRDMFE
QAKKHAPCIVFIDEIDAVGRHRGAGMGGGNDEREQTLNQMLVEMDGFEANSGVIVIAATN
RSDVLDKALLRPGRFDRQVYVGLPDIRGREHIMKVHLRKVPISNDVDAAVIARGTPGFSG
ADLANLVNEAALFAARRGKRIVEMTDFEDAKDKIFMWSGAQVGRDPRRVEARYRVSRVGP
RSHCEAAAEGRPGAQGHDHSAWPGIGRHVAVAGARQRNVLERLSA