Protein Info for ABIE53_002947 in Paraburkholderia graminis OAS925

Annotation: simple sugar transport system ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 280 PF00005: ABC_tran" amino acids 40 to 195 (156 residues), 105.8 bits, see alignment E=3e-34

Best Hits

Swiss-Prot: 40% identical to FRCA_RHIML: Fructose import ATP-binding protein FrcA (frcA) from Rhizobium meliloti

KEGG orthology group: K02056, simple sugar transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 98% identity to bug:BC1001_2454)

Predicted SEED Role

"Inositol transport system ATP-binding protein" in subsystem Inositol catabolism

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (280 amino acids)

>ABIE53_002947 simple sugar transport system ATP-binding protein (Paraburkholderia graminis OAS925)
MSDTNPVTHEAPVATAAAQQDDVILALENVNKYFGKVIALSGVTLRLKRGEVHCLLGDNG
AGKSTLIKTLAGVHQPSSGQYLVDGKPVLFESPKDALDLGIATVYQDLALVPLLSVARNF
FMGREPQKKLFGFLNVMDLETSATTARDKLAEMGINVRDPHQPIGTMSGGEKQCLAIARA
IHFGARVLILDEPTAALGVKQSFNVLKLIHKARAKGISVIFITHNVHHAYPIGDSFTLLN
RGKSLGTFTKETISKDEVLDMMAGGAEMQKMIGELEGATI