Protein Info for ABIE53_002913 in Paraburkholderia graminis OAS925

Annotation: electron-transferring-flavoprotein dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 507 PF01494: FAD_binding_3" amino acids 17 to 219 (203 residues), 26.1 bits, see alignment E=1.3e-09 PF13450: NAD_binding_8" amino acids 22 to 67 (46 residues), 24.7 bits, see alignment 5.7e-09 PF21162: ETFQO_UQ-bd" amino acids 221 to 314 (94 residues), 152.9 bits, see alignment E=7.3e-49

Best Hits

Predicted SEED Role

"Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases (EC 1.5.5.1)

Isozymes

Compare fitness of predicted isozymes for: 1.5.5.1

Use Curated BLAST to search for 1.5.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (507 amino acids)

>ABIE53_002913 electron-transferring-flavoprotein dehydrogenase (Paraburkholderia graminis OAS925)
MTPASLIEQYGPRESMEYDVVIVGGGPAGLSAAIRLKQLAAGKGVELGVCVLEKGSEIGA
HILSGAVMDPRALNELIPDWKEKGAPLTVDVTEDRFLFLTETGSKSVPNWALPDNFKNHG
NYVISLANVTRWLGQQAEALGVEIFPGFPAAEVLYNDDGSVKGVATGNLGIGKDGQPTEN
FQLGMELHAKYTLFCEGARGHLGRQLNDKFRLRDGVDPQVYGIGIKELWEIDPSKHKPGL
VMHTAGWPLQTDTYGGSFLYHMDNNQVVVGFVVGLGYTNPYLSPFEEFQRYKTHPAIRQF
LEGGKRVSYGARAITAGGLMSLPKLVFAGGALVGDDAGFLNASRIKGSHAAIKTGMLAAD
AAFEAVQAGRHNDELAAYPESFKTSWLHTELYRARNFKQWMSKGLYLGTLMVGIEQKLLG
GNVPWTLHHQHWGPRDAEARVAMHADRVSEARWQAHVRPLVFGVHLEHESRGEPARASDA
EGPDGAGERELADVCRPGSALLPGRRL