Protein Info for ABIE53_002868 in Paraburkholderia graminis OAS925

Annotation: cystine transport system ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 259 PF00005: ABC_tran" amino acids 17 to 171 (155 residues), 129.4 bits, see alignment E=1.5e-41

Best Hits

Swiss-Prot: 48% identical to TCYC_BACSU: L-cystine import ATP-binding protein TcyC (tcyC) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 95% identity to bgf:BC1003_1078)

MetaCyc: 48% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1)" in subsystem Bacterial Cell Division (TC 3.A.5.1.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (259 amino acids)

>ABIE53_002868 cystine transport system ATP-binding protein (Paraburkholderia graminis OAS925)
MIRLEKIDKYFSGHRVLDSVDLQLAQGNVTALIGPSGSGKSTLLRCVNLLEIPESGSLEI
GDQKLTFSQDERPSRETVLTIRRRTGMVFQNFQLFPHLTVRQNVMEGLLTVLKWDKEKAR
ARADELLEKVGIAHKADAWPVTLSGGQQQRVAIARALAPSPEVLLCDEPTSALDPGLAAE
VVEVLKQLASEGMTMLMATHDLRLAATIARDVVFLNNGVVVEAGPSREVFMRPRQEETAP
FCVDAHAQLAGSVDGVKRD