Protein Info for ABIE53_002816 in Paraburkholderia graminis OAS925

Annotation: MHS family proline/betaine transporter-like MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 83 to 105 (23 residues), see Phobius details amino acids 117 to 137 (21 residues), see Phobius details amino acids 141 to 164 (24 residues), see Phobius details amino acids 186 to 207 (22 residues), see Phobius details amino acids 217 to 238 (22 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details amino acids 312 to 330 (19 residues), see Phobius details amino acids 342 to 361 (20 residues), see Phobius details amino acids 369 to 392 (24 residues), see Phobius details amino acids 402 to 426 (25 residues), see Phobius details amino acids 436 to 454 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 49 to 462 (414 residues), 156.9 bits, see alignment E=8.6e-50 PF07690: MFS_1" amino acids 51 to 396 (346 residues), 116.3 bits, see alignment E=1.5e-37

Best Hits

Swiss-Prot: 52% identical to OUSA_DICD3: Glycine betaine/proline/ectoine/pipecolic acid transporter OusA (ousA) from Dickeya dadantii (strain 3937)

KEGG orthology group: K03762, MFS transporter, MHS family, proline/betaine transporter (inferred from 96% identity to bpy:Bphyt_2625)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (500 amino acids)

>ABIE53_002816 MHS family proline/betaine transporter-like MFS transporter (Paraburkholderia graminis OAS925)
MSFVAVIGVFTLTASSNGFWRHHKQEQRLSLDDITVVDKSLLKRAVGAMALGNAMEWFDF
GVYSYIAVTLGKVFFPSSSPSAQLIATFGTFAAAFLVRPVGGMVFGPLGDRIGRQRVLAM
TMIMMALGTFAIGLIPSYGSIGILAPALLLVARLVQGFSTGGEYGGAATFIAEFSTDKRR
GFMGSFLEFGTLIGYVLGAGTVAVLTATLSNEALLSWGWRVPFLIAGPLGLVGLYIRMKL
EETPAFKKQAEQREAEDKALPKQSLGNLLVQQWKPLLLCVGLVLIFNVTDYMALSYLPSY
LSATLHFNESHGLFIVLLVMVLMMPATLAAGRLSDAIGRKPVMLFGCVGLFALSIPALLL
IRMGTLLPVFSGLMILGVLLSCFTGVMPSALPALFPTKIRYGALAIGFNVSVSLFGGTTP
LVTAWLVDRTGNLMMPAYYLMGASLIGIVSVVALRETARKPLLGSGPCVATRAEAHAVLR
GEREAEEMDEGYAATATARA