Protein Info for ABIE53_002766 in Paraburkholderia graminis OAS925
Annotation: competence protein ComEC
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02238, competence protein ComEC (inferred from 77% identity to bug:BC1001_2277)Predicted SEED Role
"Predicted hydrolase of the metallo-beta-lactamase superfamily, clustered with KDO2-Lipid A biosynthesis genes" in subsystem KDO2-Lipid A biosynthesis
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (949 amino acids)
>ABIE53_002766 competence protein ComEC (Paraburkholderia graminis OAS925) MRAWWCGFALGVIWLQQQAELPGWRGGCLLVSLACAASAVAIWGLRRRAEIQSDGHSAVA HWTLRRWRSFAGWCAVCCVAWGAGFGYAAWRADVRLAASLPPAWEGRDIDVTGSIKGLPA RDDNGARFLFDVESVDSHEAGPLPPTPVIFPRVIQLAWIADEAPPPLQPGARWRLRVRLK RPHGNANFGLRDAEAALLARNVRATGYVSAAAQAVRLRPDARGVGVTVDRWRAALRARID AVLGSAPHRGIVVALAIGAQDEISDADWQLMRATGTSHLVAISGLHIGFAAGIAAWLAGA FWRRSGWIGRNWPLWLPAQIVAVTGGALFAALHAALAGFNVPVQRALWMASVVALAYVSG RNVPRSAVLAWALGLVVLIDPWAVVSAGFWLSFCAVAAILFATSGRPRVWDREQHFDEID DDGVAAGGVLAASSRASGLWRSLRFPRFRTAAARRIRAFGERLHGAAHVQFAVTLALAPL TVYWFAQIPLIGPLANAFAIPWVSVLVTPSVLAGVVLPAPLDAYAWRIAHALLDVMIAGL QRLSGPRWVLWWLPQPNAWTLAAAAAGVLWCLAPRGWPLRWAAPLTWLPLVVPAPSGPPH GSFRLTALDVGQGTSVLVETAHHALLFDAGPGPESTHAGERVVVPYLRAHGVNALDTLII SHADSDHSGGAPAVLDAIEVRQMVAALAPANALWTNARQRGADTWPCAAGQRWQWDGVEF AMLWPDPGPLQGKPNAHCCVLRVSTLPLAVASELGGAVRSAAESAGVDGTGDTDSSVRSA PTSASNTAPTGASTNAPTGASTNASNSAPTAGPTPQPQATPLAALLTADIEAPSERVLLS RDREMLRAEVLVVPHHGSKTSSTEPFLDSIDPLIALFQVGYRNRFHHPSAGVLARYSARH IELGRSDSDGAVRVLVDPYFAAREAPHAPDAALTVERYRDTQRRYWMDR