Protein Info for ABIE53_002758 in Paraburkholderia graminis OAS925

Annotation: molecular chaperone Hsp33

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 PF01430: HSP33" amino acids 3 to 291 (289 residues), 268.4 bits, see alignment E=3.8e-84

Best Hits

Swiss-Prot: 35% identical to HSLO_SODGM: 33 kDa chaperonin (hslO) from Sodalis glossinidius (strain morsitans)

KEGG orthology group: K04083, molecular chaperone Hsp33 (inferred from 97% identity to bug:BC1001_2270)

Predicted SEED Role

"33 kDa chaperonin (Heat shock protein 33) (HSP33)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (316 amino acids)

>ABIE53_002758 molecular chaperone Hsp33 (Paraburkholderia graminis OAS925)
MSDQLQKFMFSAAPVRGEIVSLRNTWQEVLTRRQYPAPVRTILGEMMAACALLSANLKFD
GTLIMQIFGDGPVKMLVVQCSSDLSMRATAKLSGDEDSVIGETTSMIELLNASGHGRCVI
TLDPRDKKPGQQPYQSIVPLSGENGPLESMAEVLEHYMHHSEQLDTRLWLAANSERAVGM
LLQKLPGDGGIVPHPGELDADTWERVCTLGGTLSQDELLKEEPETVFRRLFWQENVQHFE
PASARFECTCSREKVGSMLKMLGRDEVDGVIAERGHVEIHCEFCNQRYEFDPVDVAQLFF
ANALSQGVTPAAEQRH