Protein Info for ABIE53_002697 in Paraburkholderia graminis OAS925

Annotation: glutathione S-transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 PF02798: GST_N" amino acids 1 to 77 (77 residues), 52.3 bits, see alignment E=1.8e-17 PF13409: GST_N_2" amino acids 10 to 77 (68 residues), 60.5 bits, see alignment E=5.7e-20 PF13417: GST_N_3" amino acids 13 to 81 (69 residues), 46.6 bits, see alignment E=1e-15 PF13410: GST_C_2" amino acids 138 to 201 (64 residues), 28.9 bits, see alignment E=3e-10 PF00043: GST_C" amino acids 141 to 206 (66 residues), 21.1 bits, see alignment E=9e-08 PF14497: GST_C_3" amino acids 150 to 211 (62 residues), 23.8 bits, see alignment E=1.3e-08

Best Hits

Swiss-Prot: 60% identical to GST2_YEAST: Glutathione S-transferase 2 (GTT2) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

KEGG orthology group: None (inferred from 74% identity to cak:Caul_3933)

MetaCyc: 60% identical to glutathione transferase 2 monomer (Saccharomyces cerevisiae)
Glutathione transferase. [EC: 2.5.1.18]; 2.5.1.18 [EC: 2.5.1.18]

Predicted SEED Role

"Glutathione S-transferase (EC 2.5.1.18)" in subsystem Glutathione: Non-redox reactions (EC 2.5.1.18)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.18

Use Curated BLAST to search for 2.5.1.18

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (214 amino acids)

>ABIE53_002697 glutathione S-transferase (Paraburkholderia graminis OAS925)
MKIFDIPGFPNPLRIRIVLAEKNLASKVEFIKVDLPAAEHKQAAFLAINPTGTVPVLQLD
DGTYISECTAITEYLDNLDGNPVLTGKSPKEKALVHMMQKRAESELIDAVGIYFHHATPG
LGPALQAYKSPDWEGRREWGERSRDKAVAGMRYFDKVLTAQPYVAGESFSMADITVWAGL
VFAGFANIRVPEECTALLNWRQTVDERSSVKNPA