Protein Info for ABIE53_002392 in Paraburkholderia graminis OAS925

Annotation: OHCU decarboxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01522: Polysacc_deac_1
  • amino acids 76 to 164 (89 residues), 50.2 bits, E=2.5e-17
• PF09349: OHCU_decarbox
  • amino acids 328 to 484 (157 residues), 181 bits, E=2.4e-57
• TIGR03164: OHCU decarboxylase
  • amino acids 331 to 486 (156 residues), 223.7 bits, E=5.9e-71

Predicted SEED Role

"Uricase (urate oxidase) (EC 1.7.3.3)" (EC 1.7.3.3)

MetaCyc Pathways

• superpathway of purines degradation in plants (14/18 steps found)
• ureide biosynthesis (5/7 steps found)
• urate conversion to allantoin I (2/3 steps found)

KEGG Metabolic Maps

• Caffeine metabolism
• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.7.3.3

Use Curated BLAST to search for 1.7.3.3

Protein Sequence (489 amino acids)

>ABIE53_002392 OHCU decarboxylase (Paraburkholderia graminis OAS925)
MPLDPNYPRDLIGYGRHPVQANWPGRARVAVQFVLNYEEGGENCVLHGDPGSEQFLSEIV
GAAAYPARHMSMESIYEYGSRAGVWRILSEFEKRGLPLTVFGVGMAIERHPEVARAFVEL
GHEIACHGYRWIHYQDVSPEKEAEHMRLGMQAIERVTGERPLGWYTGRDSPNTHRLVAEY
GGFLYDSDYYGDDLPFWMDVEVTGGSTVPQLIVPVHARHQRHALREPAGLQHRGPLLHVP
ARCVRRALRRRRRSAEDAVDRHALPAARTPWAFPRTAAFSRPYRTARSRLGDTARRHRAA
LARTSSVSAKQPRGGGMKAMQYTLDQLNTVSTDAFVAALSGIFEHSPWVAEIAANERPFA
SIDELHRKMSKIVETAGEDKQLALINAHPELAGKAAVRGELTAESTREQSGAGLAQCTQA
EFDRLLALNAAYREKFGFPFILAVRGYDRHGIIANFEARVNNSRADELRASLDQIYRIAR
FRLEDLISA