Protein Info for ABIE53_002372 in Paraburkholderia graminis OAS925

Annotation: manganese transport protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 transmembrane" amino acids 21 to 39 (19 residues), see Phobius details amino acids 54 to 75 (22 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 128 to 150 (23 residues), see Phobius details amino acids 162 to 181 (20 residues), see Phobius details amino acids 203 to 223 (21 residues), see Phobius details amino acids 252 to 275 (24 residues), see Phobius details amino acids 299 to 322 (24 residues), see Phobius details amino acids 342 to 361 (20 residues), see Phobius details amino acids 367 to 387 (21 residues), see Phobius details amino acids 404 to 427 (24 residues), see Phobius details TIGR01197: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family" amino acids 24 to 396 (373 residues), 337.7 bits, see alignment E=5.6e-105 PF01566: Nramp" amino acids 44 to 401 (358 residues), 410 bits, see alignment E=4.3e-127

Best Hits

Swiss-Prot: 50% identical to MNTH2_PSEAE: Divalent metal cation transporter MntH 2 (mntH2) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03322, manganese transport protein (inferred from 95% identity to bgf:BC1003_1903)

Predicted SEED Role

"Manganese transport protein MntH" in subsystem Transport of Manganese

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (431 amino acids)

>ABIE53_002372 manganese transport protein (Paraburkholderia graminis OAS925)
MNTNPFALRPNRRRRLPEGGPAHWFSFVGAGALIAVGYIDPGNWATALGAGAGYGYQLLG
MVVLSSLMAMLLQWLSSRLGVVTGRDLAQVCRERSGPRRTIFLWLTSEVAIIACDVAEVV
GSAVALQLLLGVSLTVGVLMSAVCTFALLALQQIGGRKLEAVIALLIGFVGLCFVIELAL
ARPDWHAALAGTAPSPELLRNAGMLWLAAGIVGATVMPHNLYLHSSLVKHHAPDSSDAQI
KAALHVVNIDTIGSLLFAFVINAALLIVAAAVFHASGHRDVTDLADAHRLIAPLLGTRWA
GILFAAALLACGLSATVTGTLAGQAVMEGFLQLRLPRWKRALLTRALAIGPALVAVTMFG
QEGSNQLLVASQVVLSLQLPLAVVPLIRYASDASLMRDWRVHGVPLVLAWMSAGFIILLN
GALLWQVALGE