Protein Info for ABIE53_002000 in Paraburkholderia graminis OAS925

Annotation: glyoxylate carboligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 PF02775: TPP_enzyme_C" amino acids 24 to 184 (161 residues), 124.8 bits, see alignment E=1.4e-40

Best Hits

Predicted SEED Role

"Glyoxylate carboligase (EC 4.1.1.47)" in subsystem Allantoin Utilization or Photorespiration (oxidative C2 cycle) (EC 4.1.1.47)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.47

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (222 amino acids)

>ABIE53_002000 glyoxylate carboligase (Paraburkholderia graminis OAS925)
MKPQRVYEEMNQVFGRDTCYVSTIGLSQIAGAQFLHVYKARNWINCGQAGPLGWTIPAAL
GVRAADPQRPIVALSGDYDFQFMIEELAAGAQFKLPYVHVVVNNSYLGLIRQAQRAFDMD
FCVQLGFENINSPEMNGYGVDHVAVAEGLGCKAIRVFKPEELKPALQKAQSMLSEFNVPV
IVEVILERVTNISMGAEIDAINEFEELATTREDAPTAISIAD