Protein Info for ABIE53_001806 in Paraburkholderia graminis OAS925

Annotation: gamma-glutamylputrescine oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 436 PF01266: DAO" amino acids 37 to 392 (356 residues), 264.4 bits, see alignment E=5.5e-82 PF00890: FAD_binding_2" amino acids 37 to 223 (187 residues), 22.1 bits, see alignment E=2e-08 PF13450: NAD_binding_8" amino acids 40 to 83 (44 residues), 23.8 bits, see alignment 1.1e-08

Best Hits

KEGG orthology group: K09471, gamma-glutamylputrescine oxidase [EC: 1.4.3.-] (inferred from 86% identity to bge:BC1002_6758)

Predicted SEED Role

"Glycine/D-amino acid oxidase (deaminating) in putrescine utilization cluster"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.4.3.-

Use Curated BLAST to search for 1.4.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (436 amino acids)

>ABIE53_001806 gamma-glutamylputrescine oxidase (Paraburkholderia graminis OAS925)
MSSLLNKELGVVEDSYYEASVTRPQPSAPLQQKLSVDVCVIGGGYAGVSCALELAGRGFD
VALLEAQRIGWGASGRNGGQAIVGFGAEGEDAIEQQCSREIARKAWDVSLEGLRLLEERL
ARYDIECHYRRGYLTLAVNDRKARKLKEWMERTQDRYAYPLEWLDRSALRSHIATQRFSA
GVYDGGSGHLHPLLYCLGLGEAARQAGVKVFENSAVSRLERGARPVVKTAEGAVSCDRVV
IAGNVYLGEFGDHPAPEIEARIMPVGTYMVATEPLSDAFANELMPGRAAASDNNLILDYF
RLSADNRLLFGAGESYDATTPRNLIDRMRDRITGVFPQLADVGIDYAWGGFVDVTMNRAP
DLGRIGANIYYVQGFSGHGLVFAGMAGKILADAIAGDASTFDVFSRIRHRRFPGGKALRT
RALVLGMWYYKLRELL