Protein Info for ABIE53_001765 in Paraburkholderia graminis OAS925

Annotation: histidine transport system permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 233 transmembrane" amino acids 24 to 44 (21 residues), see Phobius details amino acids 60 to 81 (22 residues), see Phobius details amino acids 97 to 114 (18 residues), see Phobius details amino acids 135 to 152 (18 residues), see Phobius details amino acids 163 to 183 (21 residues), see Phobius details amino acids 194 to 220 (27 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 12 to 119 (108 residues), 63.6 bits, see alignment E=9.8e-22 PF00528: BPD_transp_1" amino acids 35 to 225 (191 residues), 82.4 bits, see alignment E=1.8e-27

Best Hits

Swiss-Prot: 64% identical to HISQ_SALTY: Histidine transport system permease protein HisQ (hisQ) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K10016, histidine transport system permease protein (inferred from 99% identity to bug:BC1001_1277)

Predicted SEED Role

"Histidine ABC transporter, permease protein HisQ (TC 3.A.1.3.1)" in subsystem Arginine and Ornithine Degradation (TC 3.A.1.3.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (233 amino acids)

>ABIE53_001765 histidine transport system permease protein (Paraburkholderia graminis OAS925)
METRVVLYGFGPVLLAGTIQTVELSVLSLAAAVLLGLAGAAAKLSLNRPLRALATGYTTL
IRSVPDLVLMLLLFYSIQIAVNNLTDALDVAQFDIDPFVAGVLTLGFIYGAYFTETFRGA
FLAVPRGQLEAGSAYGMSGVRVFARILFPQMMRFALPGIGNNWQVLVKATALVSIIGLAD
VVKAAQDAGKSTFNMFFFILIAALIYLALTTVSNLALIWLERRYSIGVRHAEL