Protein Info for ABIE53_001722 in Paraburkholderia graminis OAS925

Annotation: MHS family proline/betaine transporter-like MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 33 to 59 (27 residues), see Phobius details amino acids 68 to 94 (27 residues), see Phobius details amino acids 106 to 127 (22 residues), see Phobius details amino acids 133 to 158 (26 residues), see Phobius details amino acids 178 to 198 (21 residues), see Phobius details amino acids 204 to 222 (19 residues), see Phobius details amino acids 260 to 283 (24 residues), see Phobius details amino acids 296 to 316 (21 residues), see Phobius details amino acids 326 to 346 (21 residues), see Phobius details amino acids 353 to 375 (23 residues), see Phobius details amino acids 390 to 412 (23 residues), see Phobius details amino acids 420 to 439 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 34 to 229 (196 residues), 55.8 bits, see alignment E=3.9e-19 amino acids 246 to 446 (201 residues), 53 bits, see alignment E=2.7e-18 PF07690: MFS_1" amino acids 37 to 307 (271 residues), 60 bits, see alignment E=2e-20 amino acids 300 to 434 (135 residues), 43.3 bits, see alignment E=2.4e-15

Best Hits

KEGG orthology group: None (inferred from 90% identity to bug:BC1001_1249)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (448 amino acids)

>ABIE53_001722 MHS family proline/betaine transporter-like MFS transporter (Paraburkholderia graminis OAS925)
MDYSAAQHPAAHDASSDEPAHDTQRASRAKAIAAITLGNGLEFFDFTIYSFFATIIGKLY
FPVEGQLAQLMLAVGTFGVGFIMRPVGGVVLGAYADRAGRKAAMSLTLWLMTLGSAIIAF
APTYAAIGVAAPVLVIVARLVQGFALGGEVGASTSLLMEYGSDKTRGFYGSWQFVSQGMN
TVCGSLLGVALAAALSTAALESWGWRVPFVIGMAMGPIGIYIRRHLNETLPGVEDGNAPV
NADAATQPVRKLFRDHSRSIAAGVVTTIGGTAANYIVLFYLSTYAIRILHLPMSSALWAA
WTAAAVTVVCSPFAGALSDRVGRKPVLLVSRVLLIAAVYPAFIAINASPTVPVLLAVVAA
LAVLVAFTAVPNIVMLPELFPREIRATGMSIVYCLGVSIFGGFAQFFATWLIQLSGSNLA
PAWYLIGCGLVSLVPLPFMRETAGRAID