Protein Info for ABIE53_001096 in Paraburkholderia graminis OAS925

Annotation: sigma-B regulation protein RsbQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 PF12146: Hydrolase_4" amino acids 17 to 246 (230 residues), 38.6 bits, see alignment E=1.1e-13 PF00561: Abhydrolase_1" amino acids 18 to 250 (233 residues), 59 bits, see alignment E=9.1e-20 PF12697: Abhydrolase_6" amino acids 19 to 254 (236 residues), 88.4 bits, see alignment E=1.7e-28

Best Hits

Swiss-Prot: 49% identical to RSBQ_BACSU: Sigma factor SigB regulation protein RsbQ (rsbQ) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 70% identity to bpy:Bphyt_5295)

Predicted SEED Role

"Hydrolase of unknown specificity RsbQ, part of a novel [RsbQ - PAS domain] bacterial sensing module"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (267 amino acids)

>ABIE53_001096 sigma-B regulation protein RsbQ (Paraburkholderia graminis OAS925)
MNIHQRNNVNVIGEGARTLVFAHGFGCDQNMWRRLVPTFSDRFRIVLFDLVGCGQSDLSA
YDRDRYSSLHGYAADVLEIVADVAEGPVIFVGHSVSAIIGLLAEIEAPDRFAAQIMIGPS
PSYINDGDYIGGFSREDIEGLLETMDGNYLGWSSTMAPAIMGAPDQPELGEELTNSFCRT
DPEIASHFARVTFLSDHRNDLRRIDSPVLLLQCSDDLIAPRPVGDYMHRVMRNSTLRIIE
NVGHCPHLSAPAASIDAMEEFLKQLEG