Protein Info for ABIE53_001025 in Paraburkholderia graminis OAS925

Annotation: ESS family glutamate:Na+ symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 460 transmembrane" amino acids 61 to 83 (23 residues), see Phobius details amino acids 94 to 115 (22 residues), see Phobius details amino acids 126 to 146 (21 residues), see Phobius details amino acids 154 to 179 (26 residues), see Phobius details amino acids 185 to 205 (21 residues), see Phobius details amino acids 220 to 244 (25 residues), see Phobius details amino acids 276 to 299 (24 residues), see Phobius details amino acids 305 to 324 (20 residues), see Phobius details amino acids 333 to 355 (23 residues), see Phobius details amino acids 362 to 385 (24 residues), see Phobius details amino acids 395 to 417 (23 residues), see Phobius details amino acids 429 to 456 (28 residues), see Phobius details PF03616: Glt_symporter" amino acids 63 to 426 (364 residues), 487.7 bits, see alignment E=9.4e-151 TIGR00210: sodium/glutamate symporter" amino acids 63 to 457 (395 residues), 565.9 bits, see alignment E=2e-174

Best Hits

Swiss-Prot: 66% identical to GLTS_SHIFL: Sodium/glutamate symporter (gltS) from Shigella flexneri

KEGG orthology group: K03312, glutamate:Na+ symporter, ESS family (inferred from 71% identity to mms:mma_1604)

MetaCyc: 66% identical to glutamate:sodium symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-122

Predicted SEED Role

"Sodium/glutamate symport protein" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (460 amino acids)

>ABIE53_001025 ESS family glutamate:Na+ symporter (Paraburkholderia graminis OAS925)
MVLPVSTRPIPAHRDVLPNDQASNTQASTKHLLPDGRCVLSTISCATDRSCANVTLRRIP
IVSLDTLETLMAASLVLVLGRQILARISILRTYSIPEPVVGGLLIALLVFALRNTLQIDV
RFDTTLQVPLMLSFFATIGLNANLASLKAGGRSLIVFLGVVVGLLVMQNVLGIGLAWALG
QERILGLLGASVTLSGGHGTGAAWAKVFAERHGLQAATEIAIACATFGLILGGLIGGPVA
RFLVTRYGLAPNREPDVADTTGFEQPKAVRAITADAVIETVALIAVCLAVGSALASWLTG
TALELPPFVCVLFVGIMLRNGFAVTDWYQVSELAVSLLGNVSLALFLAIALMSLRLGDLA
SLALPLFAILVVQAIAMAGYAIFVTFRVMGRNYDAAVLAAGHCGFGLGATPTAIANMQAI
TERFGPSHLAFLVVPMVGAFFIDIANAIVIKLFLLLPMYG