Protein Info for ABIE53_000862 in Paraburkholderia graminis OAS925

Annotation: molecular chaperone GrpE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 195 PF01025: GrpE" amino acids 43 to 192 (150 residues), 170.8 bits, see alignment E=1.1e-54

Best Hits

Swiss-Prot: 92% identical to GRPE_PARXL: Protein GrpE (grpE) from Paraburkholderia xenovorans (strain LB400)

KEGG orthology group: K03687, molecular chaperone GrpE (inferred from 96% identity to bgf:BC1003_0462)

Predicted SEED Role

"Heat shock protein GrpE" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (195 amino acids)

>ABIE53_000862 molecular chaperone GrpE (Paraburkholderia graminis OAS925)
MENTQENPTSQNPTPADETERPAAEAVTPEQEAAASVATDTPAATGAEAALAEAQAKIAE
LQESFLRAKAETENVRRRAQEDVAKAHKFAIESFAEHLLPVIDSLEAAVAHSSDDLAKVR
EGVELTLRQLTGALEKGRVVALNPVGEKFDPHRHQAISMVPADQEPNTVVAVLQKGFVIA
DRVLRPALVTVAAPK