Protein Info for ABIE53_000757 in Paraburkholderia graminis OAS925

Annotation: N-acyl-D-amino-acid deacylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 493 PF07969: Amidohydro_3" amino acids 50 to 250 (201 residues), 80.5 bits, see alignment E=2e-26 amino acids 337 to 464 (128 residues), 74.8 bits, see alignment E=1e-24 PF01979: Amidohydro_1" amino acids 389 to 461 (73 residues), 26.7 bits, see alignment E=3.4e-10

Best Hits

Swiss-Prot: 49% identical to NDAD_ALCXX: D-aminoacylase (dan) from Alcaligenes xylosoxydans xylosoxydans

KEGG orthology group: K06015, N-acyl-D-amino-acid deacylase [EC: 3.5.1.81] (inferred from 97% identity to bgf:BC1003_0361)

Predicted SEED Role

"D-aminoacylase (EC 3.5.1.81)" (EC 3.5.1.81)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.81

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (493 amino acids)

>ABIE53_000757 N-acyl-D-amino-acid deacylase (Paraburkholderia graminis OAS925)
MHSHPEAADTLIVGAQLYDGTGAPPVERDVAVRDGRIVAIGNLSNWLAEDVIEAEGRALA
PGFIDVHTHDDTHVIRSPQMLPKITQGVTTVIVGNCGISASPVALKGDPPDPMNLLGERD
AFQYPTFADYVKAVNAARPAVNVGALIGHTALRNNQMDRLDRAATPQEIEGMRAQLEEAL
ANGALGLSSGLAYGSAFAAPTEEVMALAEPLAAAGALYTTHMRTEFDAILDAMDEAYRVG
RHARVPVIISHLKCAGPSNWGRSVEVLNSLEGARRMQPIGCDCYPYNRSSSTLDLKQVTG
DIDITITWSEPHPEMAGKLVKEIAAEWGVTQQEAGKRLQPAGAVYHNMSEDDVRRILSHP
ATMVGSDGLPNDPLPHPRLWGAFPRVLGHYARDAGLLPLEEAVRKMTSLSARRFGLAQRG
EVHIGYHADLVLFDPAKVRDAATFEKPQQAADGIDAVWVNGVLSYLNGEVTGERAGHFVA
RGAASKGDAEGAF