Protein Info for ABIE53_000753 in Paraburkholderia graminis OAS925

Annotation: EmrB/QacA subfamily drug resistance transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 517 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 44 to 62 (19 residues), see Phobius details amino acids 74 to 99 (26 residues), see Phobius details amino acids 105 to 124 (20 residues), see Phobius details amino acids 135 to 158 (24 residues), see Phobius details amino acids 164 to 183 (20 residues), see Phobius details amino acids 196 to 216 (21 residues), see Phobius details amino acids 222 to 243 (22 residues), see Phobius details amino acids 264 to 287 (24 residues), see Phobius details amino acids 300 to 318 (19 residues), see Phobius details amino acids 330 to 350 (21 residues), see Phobius details amino acids 356 to 379 (24 residues), see Phobius details amino acids 399 to 420 (22 residues), see Phobius details amino acids 476 to 496 (21 residues), see Phobius details PF07690: MFS_1" amino acids 14 to 408 (395 residues), 188.9 bits, see alignment E=1.9e-59 PF06609: TRI12" amino acids 27 to 429 (403 residues), 36.5 bits, see alignment E=3.2e-13 PF00083: Sugar_tr" amino acids 44 to 180 (137 residues), 33.3 bits, see alignment E=4e-12

Best Hits

KEGG orthology group: None (inferred from 96% identity to bug:BC1001_0346)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (517 amino acids)

>ABIE53_000753 EmrB/QacA subfamily drug resistance transporter (Paraburkholderia graminis OAS925)
MPFRESLLAMLGISFVTMLVALDQTVVGTALPTIVAELKGFELYAWVATSYLLTSVITVP
IFGRLGDYYGRKPFVIASIVVFTAASVLCGMANNMLFLVLARGLQGIGGGMLVGTAFACI
PDLFPDSVVRLRWQVLMSSAFGIANAVGPSLGGFLTQYYGWRSVFYVNLPVGLLSLFFVW
RFLPHLRHVEHEGKMRLDWPGAALIAVALGSLQLFVELLPKHGLTLSACALLVLSAASAY
ALWQWEKRCPTAILPVDMFRNPSLAALFTLAVLGGFTMFSLLFYAPLLFQGGFGMSPKEA
GVVITPLVVFITIGSIANGRVVSRVRNPNLMLYVGFALIALACFGVVVATRSMPHWLLMS
FMVLGGLGLGFVMPNLTIFAQQTAGREHLGIATALLQSLRMIGGMIGTALTGTLISHMYA
SGVRSALESDRASQWFSDLGDPQILINHEAQTTLLGELAQAGHNGAMLLETARETLVSAI
HFGLAMAAVVAVVSVWQSRRVPPIKLQRKLEPVVHAD