Protein Info for ABIE53_000673 in Paraburkholderia graminis OAS925

Annotation: cytochrome c oxidase subunit 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 544 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 51 to 78 (28 residues), see Phobius details amino acids 99 to 116 (18 residues), see Phobius details PF02790: COX2_TM" amino acids 36 to 116 (81 residues), 61.7 bits, see alignment E=1.5e-20 TIGR02866: cytochrome c oxidase, subunit II" amino acids 43 to 266 (224 residues), 195.6 bits, see alignment E=3.6e-62 PF00116: COX2" amino acids 131 to 256 (126 residues), 111.7 bits, see alignment E=5e-36 PF13442: Cytochrome_CBB3" amino acids 290 to 360 (71 residues), 49.7 bits, see alignment E=9.8e-17 PF00034: Cytochrom_C" amino acids 291 to 352 (62 residues), 31.3 bits, see alignment E=1.1e-10 PF00691: OmpA" amino acids 443 to 516 (74 residues), 50.8 bits, see alignment E=4.5e-17

Best Hits

KEGG orthology group: K02275, cytochrome c oxidase subunit II [EC: 1.9.3.1] (inferred from 96% identity to bgf:BC1003_0278)

Predicted SEED Role

"Cytochrome c oxidase polypeptide II (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (544 amino acids)

>ABIE53_000673 cytochrome c oxidase subunit 2 (Paraburkholderia graminis OAS925)
MKTIKRALMGVLAMSGLLFAGAALAVGDVPGGPAVNEINLQPPATKIAEELYSLHTLMLI
LCTVIFIGVFAVMFYSIFAHRKSKGHKASNFHESTTVEIIWTIVPFIIVVLMALPATKTV
VAMKDTTNADVTIKVTGYQWKWGYDYVKGPGEGISFLSTLATPRSETDGRQPISTTYLQE
VDNPLVVPVGKKIRIITTANDVVHSWYVPAFGVKQDAIPGFVRDTWFKAEKVGTFRGFCT
ELCGKEHAFMPVVVEVLSTDDYAKWVDAQKKKMAAGQDDPNKTYTMAELMERGGKVYAAN
CAVCHQPTGKGAGAFPALDGSKVANGAIAEHVSIVLKGKNAMPSWAPTLNDVEIASVVTF
ERNSWGNHTGDILQPKQVADARNGKLPEGGNHLADAGAAASGAAASGAAASEASGAQAAG
AQAASAGSESAGASQAALPASVYFDTGKSTLPADAKAAVEAASAYAKAHPDAKFTLSGFT
DASGSADTNAKLAKSRAEAVRDALKAAGIAEDHIILKKPETITGGGDAKEARRVEISAAA
SPAA