Protein Info for ABIE53_000647 in Paraburkholderia graminis OAS925

Annotation: two-component system C4-dicarboxylate transport sensor histidine kinase DctB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 666 transmembrane" amino acids 43 to 65 (23 residues), see Phobius details amino acids 330 to 350 (21 residues), see Phobius details PF00512: HisKA" amino acids 420 to 480 (61 residues), 38.3 bits, see alignment 1.1e-13 PF02518: HATPase_c" amino acids 543 to 650 (108 residues), 85.6 bits, see alignment E=3.3e-28

Best Hits

KEGG orthology group: K10125, two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC: 2.7.13.3] (inferred from 95% identity to bgf:BC1003_0253)

Predicted SEED Role

"Signal transduction histidine kinase regulating C4-dicarboxylate transport system (EC 2.7.13.3)" (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (666 amino acids)

>ABIE53_000647 two-component system C4-dicarboxylate transport sensor histidine kinase DctB (Paraburkholderia graminis OAS925)
MQPVNARPTPVPSAGEAQADGASPYATISDPTRPDSANVTRRLLILFALVAGLVAACGLT
YSVAWQSGIDSLRLNAAGRVDRTASSLKSTLERYESLPYLLAEHPIVQDVLVDPSPANVE
RANLYLEDLNRHARATVTYIIPLDGYCVAASNWQGPGSFIGAGYQFRPYFVDAIKGGVGR
FFGIGTISQAPGYYISQPVRRDGKIVGAAVVKLDLEWFQGSDASEPLLVTDDHGVIFLSS
VPAWKYHTIRPLSGQVADSIYQARQYAQQPIAPLPVTIERKLEGDAQIVRVGGGRYAPRY
LASRRGMGEPDWHLITMAPVSPVDADARNATIVTGFGYVSLVLLAFYWRMRRSRVREVMR
SRTLLQKAYAELNQRVAERTADLSQANEQLQKEVAERTRAEQELRAAHDELIQASKLAAL
GQMAAGITHELNQPLAALRGFSDNTRVLLERGDQASARENLEAIAALTERMGKITNQLKL
FVGRARPRSARASAVRALRNALALLQKRFQGVELQLALFDVESGTRTPLDLADDHPGLIA
HCDDLRLEQVLINLLGNALDATAGMSAPRISVHIEVASDNLSFAVGDNGPGIAEDVLPRL
FEPFFTTKEMGQGLGLGLAISSSIARDCGGTLVARNAPQGGALFVLTLRRARVQTSPTAD
PLTTGS