Protein Info for ABIE53_000646 in Paraburkholderia graminis OAS925

Annotation: aerobic C4-dicarboxylate transport protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 transmembrane" amino acids 25 to 45 (21 residues), see Phobius details amino acids 60 to 82 (23 residues), see Phobius details amino acids 94 to 116 (23 residues), see Phobius details amino acids 167 to 185 (19 residues), see Phobius details amino acids 198 to 223 (26 residues), see Phobius details amino acids 242 to 266 (25 residues), see Phobius details amino acids 323 to 337 (15 residues), see Phobius details amino acids 365 to 391 (27 residues), see Phobius details PF00375: SDF" amino acids 26 to 418 (393 residues), 375.4 bits, see alignment E=1.7e-116

Best Hits

Swiss-Prot: 95% identical to DCTA_PARP8: C4-dicarboxylate transport protein (dctA) from Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)

KEGG orthology group: K11103, aerobic C4-dicarboxylate transport protein (inferred from 97% identity to bug:BC1001_0241)

MetaCyc: 62% identical to C4 dicarboxylate/orotate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-121; TRANS-RXN-121A; TRANS-RXN-121C; TRANS-RXN-122A; TRANS-RXN0-451; TRANS-RXN0-517; TRANS-RXN0-553

Predicted SEED Role

"Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate, aspartate"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (443 amino acids)

>ABIE53_000646 aerobic C4-dicarboxylate transport protein (Paraburkholderia graminis OAS925)
MMRSVAGHGLTHIAGNIVKKPIHKVLYVQVIVAIIIGIALGHFYPTFAVDMKPLGDAFIK
LIKMVIGPIIFCTVVTGIAGMEDMKKVGRVGGKALLYFEIVSTFALLLGLAATHLLRPGV
GFNVDPATLNGKEVASYAAKAHGQTTVDFLMHIIPDTLVSAFSQGEILQILLIALLFGAV
LAHIGERGKPVTSFIESLSSILFGMVGIITKLAPIGAFGAMAFTIGKYGIGSLLPMLKLI
GTFYLTAIVFVVVVLGAIARAVGFNILRFIAYIKEEMLIVLGTSSSEAALPQLMLKLEKL
GCSRSVVGLVVPTGYSFNLDGTNIYMTMAVLFIAQATNTDLTWTQQLTLLAVTMLTSKGA
SGVTGAGFITLAATLAVVPTIPLSGMVLILGIDRFMSECRALTNIVGNGVATVVVSAWEK
ELDRSKLEAALRGDVPVDEPASV