Protein Info for ABIE53_000145 in Paraburkholderia graminis OAS925

Annotation: dTDP-4-amino-4,6-dideoxygalactose transaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 381 PF01041: DegT_DnrJ_EryC1" amino acids 30 to 378 (349 residues), 340.3 bits, see alignment E=1.5e-105 PF00155: Aminotran_1_2" amino acids 42 to 330 (289 residues), 26 bits, see alignment E=5.3e-10

Best Hits

Swiss-Prot: 63% identical to VIOA_SHIDY: dTDP-4-amino-4,6-dideoxy-D-glucose transaminase (vioA) from Shigella dysenteriae

KEGG orthology group: None (inferred from 83% identity to bgf:BC1003_3393)

Predicted SEED Role

"Aminotransferase, DegT/DnrJ/EryC1/StrS family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (381 amino acids)

>ABIE53_000145 dTDP-4-amino-4,6-dideoxygalactose transaminase (Paraburkholderia graminis OAS925)
MNASLPAEAVSALTEETIFVTQPYLSPLDDFIPYLREIWDSKVLTNGGPFHQRLEAALEE
YLGVDHLALFSNGTLGLVTALQALRITGEVITTPYSFVATAHSLLWNGIKPVFVDVDPHT
LNMDPRKIEAAITPQTTAILPVHCYGYPCDTEAIQKIADNYNLKVIYDAAHAFGVRTGGG
SVLRHGDLSVLSFHATKIFNTFEGGAIICPDAKTKQRVNHLKNFGFVDETTVVAPGINGK
MSEVNAAFGLLQLKNIDEALASRRDIASQYCALLSDVPGIRCLPACDSPIANRAYFPILV
EDDFPCSRDALFERLRQHKIIVRRYFYPLISDFPMYRGLVSANPANLPVAADAARKVLCL
PIYPGLSTANVERIVDIIKTY