Protein Info for ABIE51_RS19195 in Lysobacter sp. OAE881

Annotation: cytochrome c oxidase assembly protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 204 transmembrane" amino acids 22 to 45 (24 residues), see Phobius details PF04442: CtaG_Cox11" amino acids 39 to 182 (144 residues), 168.7 bits, see alignment E=4.7e-54

Best Hits

KEGG orthology group: K02258, cytochrome c oxidase subunit XI assembly protein (inferred from 68% identity to xal:XALc_0403)

Predicted SEED Role

"Cytochrome oxidase biogenesis protein Cox11-CtaG, copper delivery to Cox1" in subsystem Biogenesis of cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (204 amino acids)

>ABIE51_RS19195 cytochrome c oxidase assembly protein (Lysobacter sp. OAE881)
MNGAQGQHESAPAAPARKSAGLAKMVVVAIGAFALTFALVPLYRIACEKVFGIRLERTAS
EGVQDATAAAKRVITVQFDGGVNSKLPWDFSPNQVTMQVVPGELYETTYHARNTSERTVV
GSAVPSVAPARASGYFSKTECFCFTAQTLKAGEVRDMPVRFIVDPNLPADVKTITLSYTF
FKNDTLTAQAQGTAQAAPVPLSAP