Protein Info for ABIE51_RS17615 in Lysobacter sp. OAE881

Annotation: TolC family outer membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 472 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details TIGR01844: type I secretion outer membrane protein, TolC family" amino acids 26 to 458 (433 residues), 361.8 bits, see alignment E=2.6e-112 PF02321: OEP" amino acids 30 to 227 (198 residues), 99.1 bits, see alignment E=1.4e-32 amino acids 253 to 443 (191 residues), 125.1 bits, see alignment E=1.5e-40

Best Hits

Predicted SEED Role

"Type I secretion outer membrane protein, TolC precursor" in subsystem Multidrug Resistance Efflux Pumps or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (472 amino acids)

>ABIE51_RS17615 TolC family outer membrane protein (Lysobacter sp. OAE881)
MIRRPLVIALAAAVSLSALLPATASAEDLLQTYELARTADPQLAAAESNRLAIREGQVQT
RAAMLPQIDGSASITKGRSYSRGNNSVNADGTINPGDSDTESTTRSTGVNLSQMVYDRGN
FTRHKSAKALAQAADFQLAASGNDLITRTSAAYFNVLIALESLAAAEAAETALKKQFDYA
SKRLEVGLAPITDVHEARAQYDSARANTILARNAVEDSYQALAEITGQQVRNIKGLPKDY
QPSLTESRDADGWVSTAIENNPALRAKELQVSSTEADVETARAGHWPRLYLSGSYGDSTT
WGERDILDATRDIDSRTFGPQVGLTLSVPIFSGGATQSGVRQALARRDVAADELEQQKRL
LVRNTRNAYQTLVASISEVEARRLALVSAQAAYDASQVGLEVGTRTVLDVLQNQNNLFTA
QLEFARARYNHLQSRLLLEQAAGTLDIADVQDVNRLLTVDTASQLPAGDVPG