Protein Info for ABIE51_RS16880 in Lysobacter sp. OAE881

Annotation: chemotaxis protein CheA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 585 PF01627: Hpt" amino acids 8 to 106 (99 residues), 60 bits, see alignment E=4.2e-20 PF02895: H-kinase_dim" amino acids 196 to 253 (58 residues), 52.5 bits, see alignment 1.1e-17 PF02518: HATPase_c" amino acids 302 to 441 (140 residues), 73.8 bits, see alignment E=3e-24 PF01584: CheW" amino acids 448 to 572 (125 residues), 88.2 bits, see alignment E=7.7e-29

Best Hits

KEGG orthology group: K03407, two-component system, chemotaxis family, sensor kinase CheA [EC: 2.7.13.3] (inferred from 64% identity to xal:XALc_1376)

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (585 amino acids)

>ABIE51_RS16880 chemotaxis protein CheA (Lysobacter sp. OAE881)
MSAIANDIAADFLIEAREILDQLGEQMVALEHAHTDRDALNAVFRGFHTIKGGAGFLDFG
PMVEICHAVEDRLNVARDGTVPMDAEAFDGAQQSLDLLVDMLAAISNGEEPEHAPPALLK
SLRDGTGAGATHMPTLSPKPAKAAPAHGDLDAEFDAMLDQLHGAPGTAPKPAAAPAPARQ
AKAPAANAPAKAEDPTVRVDVRRLDAMVDLVGELVLARNRLKTIRPRLRDEDLDRAVTAL
DVATSRLQSAVMMVRMQPVGRVFARFPKLARDVARQVKKSVELEIVGAETELDRNLVEAL
ADPLVHLVRNAIDHGIESPEARRAAGKPEQGTVRLSAQQEGDHVSIEVSDDGAGIDPEKI
RRSAIKKGLIDSDAAARLTSDECLNLIFMAGFSTRSEVSDLSGRGVGMDVVQSKIRELSG
QVQIHSEVGRGSRFAIRVPLTLAILPTLLIELEEDVYALPLVRVVEVLAHDRIEPLWVDG
QRMLDLRDQPLPLIELRTWLGLAPQPGAATTCVVLQSGDSRFCLTVDRVRGREEVVIKAL
PRTLRGLAGYAGASLVGDGRMALILDVDALLRTGLRGSSSAGRDR