Protein Info for ABIE51_RS16455 in Lysobacter sp. OAE881

Annotation: class I SAM-dependent methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 PF00891: Methyltransf_2" amino acids 25 to 154 (130 residues), 27.3 bits, see alignment E=7.6e-10 PF01209: Ubie_methyltran" amino acids 44 to 154 (111 residues), 34.5 bits, see alignment E=4.9e-12 PF13847: Methyltransf_31" amino acids 46 to 153 (108 residues), 51.1 bits, see alignment E=4.4e-17 PF13489: Methyltransf_23" amino acids 46 to 202 (157 residues), 45.8 bits, see alignment E=2e-15 PF08242: Methyltransf_12" amino acids 49 to 144 (96 residues), 58 bits, see alignment E=4.5e-19 PF13649: Methyltransf_25" amino acids 49 to 144 (96 residues), 67.2 bits, see alignment E=6e-22 PF08241: Methyltransf_11" amino acids 49 to 148 (100 residues), 75.7 bits, see alignment E=1.3e-24

Best Hits

KEGG orthology group: K00599, [EC: 2.1.1.-] (inferred from 78% identity to xac:XAC0815)

Predicted SEED Role

"Methyltransferase (EC 2.1.1.-)" (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (278 amino acids)

>ABIE51_RS16455 class I SAM-dependent methyltransferase (Lysobacter sp. OAE881)
MSDTSSSCSDFPYLHGFSSTEQARLVKQARLAESTIFHDIDYSNARRLLEVGSGVGAQTE
ILLRRFPELHATCVDLNEAQLDAARTNLDAMPWLKGRYELHQSDATNLPFEPRTFDAAFL
CWVLEHVPSPARVLNEVRRVLAPGSPVYITEVMNSSFLLDPYSPNVWRYWMAFNDFQYDS
GGDPFVGAKLGNLLLAGGFRDVTTDVKTFYFDNREPARRKTMIAFWEELLLSAADQLIQA
GKVTQDVVDGMRREMHQVQNDPNAVFFYAFVQARAVVY