Protein Info for ABIE51_RS16210 in Lysobacter sp. OAE881

Annotation: peptide chain release factor 3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 534 TIGR00503: peptide chain release factor 3" amino acids 2 to 527 (526 residues), 845.5 bits, see alignment E=1.4e-258 PF00009: GTP_EFTU" amino acids 10 to 276 (267 residues), 168.7 bits, see alignment E=2.3e-53 TIGR00231: small GTP-binding protein domain" amino acids 14 to 158 (145 residues), 70.9 bits, see alignment E=1.1e-23 PF03144: GTP_EFTU_D2" amino acids 312 to 378 (67 residues), 32.9 bits, see alignment E=1.4e-11 PF16658: RF3_C" amino acids 385 to 512 (128 residues), 161.5 bits, see alignment E=1.9e-51

Best Hits

Swiss-Prot: 89% identical to RF3_XANCB: Peptide chain release factor 3 (prfC) from Xanthomonas campestris pv. campestris (strain B100)

KEGG orthology group: K02837, peptide chain release factor 3 (inferred from 90% identity to psu:Psesu_0753)

Predicted SEED Role

"Peptide chain release factor 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (534 amino acids)

>ABIE51_RS16210 peptide chain release factor 3 (Lysobacter sp. OAE881)
MSDVSLEAARRRTFAIISHPDAGKTTLTEKLLLFGGAIQMAGSVKGRKAARHATSDWMAL
EKERGISVTSSVMQFPYEGSIVNLLDTPGHADFGEDTYRVLTAVDSALMVIDVAKGVEER
TIKLMEVCRLRDTPIMTFINKLDREGKNPIELLDEVESVLKIQCAPITWPIGMGQRLKGV
VHLVTGEVHLYEQGRNFTRQDSTIFPSIDDPALEARIGAQMLQELRDELELVEGASHPFD
VAKYLAGEQTPVFFGSAVNNFGVQLLLDFFVEHAPSPKPRATTSREVAAYEPKLTGFVFK
IQANMDPQHRDRVAFMRVCSGKFSAGMKAFHVRSGKEVKLANALTFMASDREIAESAWPG
DVIGIHNHGTISIGDTFTEGENLSFTGIPNFAPELFRRARLRDPLKLKQLQKGLAQLSEE
GATQFFRPLMSNDLILGAVGVLQFDVVAYRLKDEYGVDASFEQVSVATARWIRCDNEKKL
EEFRDKNAMNLALDAAGQLVYLAPTRVNLQLAQERAPDVTFLATREHAHAAAFD