Protein Info for ABIE51_RS15380 in Lysobacter sp. OAE881

Annotation: Grx4 family monothiol glutaredoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 106 TIGR00365: monothiol glutaredoxin, Grx4 family" amino acids 4 to 101 (98 residues), 144.5 bits, see alignment E=4.5e-47 PF00462: Glutaredoxin" amino acids 16 to 81 (66 residues), 71.6 bits, see alignment E=2.6e-24

Best Hits

Swiss-Prot: 52% identical to GLRX4_ECO57: Glutaredoxin 4 (grxD) from Escherichia coli O157:H7

KEGG orthology group: K07390, monothiol glutaredoxin (inferred from 86% identity to xca:xccb100_1661)

Predicted SEED Role

"Glutaredoxin-related protein" in subsystem Glutaredoxins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (106 amino acids)

>ABIE51_RS15380 Grx4 family monothiol glutaredoxin (Lysobacter sp. OAE881)
MSVMERIQAEVESHPIVLFMKGTAQFPMCGFSSRAVQALKAAGATQLHTVNVLEDPEIRA
NLPRYSNWPTFPQLFIHGELIGGCDITLELFESGELARMISETHNQ