Protein Info for ABIE51_RS15375 in Lysobacter sp. OAE881

Annotation: SDR family NAD(P)-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF00106: adh_short" amino acids 7 to 199 (193 residues), 117.8 bits, see alignment E=8.9e-38 PF08659: KR" amino acids 9 to 180 (172 residues), 47 bits, see alignment E=5.8e-16 PF01370: Epimerase" amino acids 9 to 119 (111 residues), 24.6 bits, see alignment E=3.1e-09 PF13561: adh_short_C2" amino acids 13 to 204 (192 residues), 99.5 bits, see alignment E=4.6e-32

Best Hits

KEGG orthology group: None (inferred from 70% identity to psu:Psesu_0843)

MetaCyc: 45% identical to CAI-1 synthase (Vibrio cholerae O1 biovar El Tor str. N16961)
1.1.1.-

Predicted SEED Role

"Short chain dehydrogenase"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (247 amino acids)

>ABIE51_RS15375 SDR family NAD(P)-dependent oxidoreductase (Lysobacter sp. OAE881)
MSPLEGRVVLVTGAHGGLGAAAAQACARAGATVVLLGRKVPKLNRVYDALAQVGPEPLLY
PLDLEGASADDYAELAQRIEAELGRLDGVLHCAADFAGLTPLAQTDPAAFARALHVNLTA
PWWLTQACLPLLAKSDDASLVFVVDDAARAGQAFWGGYGLAQQGLEGLVHMLHAEMPNSS
IRVAGLRPGPMRTALRAKAYVEENDRAALDPSAYAASCVTLLSAAGAAHRGQVWIPTPAA
VGLTQLQ