Protein Info for ABIE51_RS15310 in Lysobacter sp. OAE881

Annotation: excinuclease ABC subunit UvrB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 677 TIGR00631: excinuclease ABC subunit B" amino acids 10 to 671 (662 residues), 1055.9 bits, see alignment E=0 PF04851: ResIII" amino acids 19 to 92 (74 residues), 40.4 bits, see alignment E=9.1e-14 PF00270: DEAD" amino acids 22 to 91 (70 residues), 25.1 bits, see alignment E=4.1e-09 PF17757: UvrB_inter" amino acids 164 to 254 (91 residues), 104.4 bits, see alignment E=8.3e-34 PF00271: Helicase_C" amino acids 444 to 550 (107 residues), 71.8 bits, see alignment E=1.6e-23 PF12344: UvrB" amino acids 557 to 598 (42 residues), 69.4 bits, see alignment 5.7e-23 PF02151: UVR" amino acids 640 to 672 (33 residues), 35 bits, see alignment (E = 2.7e-12)

Best Hits

Swiss-Prot: 79% identical to UVRB_XANCB: UvrABC system protein B (uvrB) from Xanthomonas campestris pv. campestris (strain B100)

KEGG orthology group: K03702, excinuclease ABC subunit B (inferred from 79% identity to xcv:XCV2812)

MetaCyc: 72% identical to UvrABC excision nuclease subunit B (Escherichia coli K-12 substr. MG1655)
3.1.25.-

Predicted SEED Role

"Excinuclease ABC subunit B" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (677 amino acids)

>ABIE51_RS15310 excinuclease ABC subunit UvrB (Lysobacter sp. OAE881)
MNDSLHPAGFQLVSSYQPAGDQPQAIERLVAGFENGLAAQTVLGVTGSGKTFTVANVVAQ
VQKPTIVMAPNKTLAAQLYGEFKSFFPHNAVEYFVSYYDYYQPEAYVPSSDTFIEKDSSV
NEHIEQMRLSATKALLERRDALIVCTVSAIYGLGDPNEYFRMVLHMVRGERIDQRELIRR
LTEMQYTRNDTELRRATYRVRGEVVDVHPAESDAEALRIELFDGEIERLTLFDPLTGESL
RQVPRYTIYPGSHYVTTRRTVLDAVETIKEELRERLEQLYAQNKLVEAQRLAQRTQFDLE
MLAEVGFCNGVENYSRHLTGHMPGEPPPCLFDYLPPDALLVVDESHVTVPQIGAMYKGDR
SRKETLVEFGFRLPSALDNRPLRFEEWEGRSPRAIYVSATPGPYELEKSEDQIVELVVRP
TGLIDPEVEIRPVATQVDDVLGEINERVKMGDRVLITTLTKRMAENLTEYLGEHGVRVRY
LHSDVDTVERVEIIRDLRLGKFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSAGSL
IQTIGRAARNVRGKAILYADRVTRSMQAALDETDRRRQRQVKHNLEHGITPRSVAKPIVD
IMEGARPEPGEVGKGRGKGKKVGESLADYAKLTPAQFAARIKALEQQMYEHAKNLEFEEA
AAVRDQLRQLKDAGFAA