Protein Info for ABIE51_RS14940 in Lysobacter sp. OAE881

Annotation: GIY-YIG nuclease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 89 PF01541: GIY-YIG" amino acids 11 to 78 (68 residues), 52.1 bits, see alignment E=3.3e-18

Best Hits

Swiss-Prot: 64% identical to Y5558_CUPNJ: UPF0213 protein Reut_B5558 (Reut_B5558) from Cupriavidus necator (strain JMP 134 / LMG 1197)

KEGG orthology group: K07461, putative endonuclease (inferred from 62% identity to dar:Daro_2472)

Predicted SEED Role

"COG2827: putative endonuclease containing a URI domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (89 amino acids)

>ABIE51_RS14940 GIY-YIG nuclease family protein (Lysobacter sp. OAE881)
MSSDADIAAPWYVYLLECRDGSLYTGITTDVARRYAQHLAGKGARYTRSRPPVRLLGQFP
HPDRASASRAEHAIKQLRPEQKRALCAGA