Protein Info for ABIE51_RS14645 in Lysobacter sp. OAE881

Annotation: multidrug effflux MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 signal peptide" amino acids 14 to 14 (1 residues), see Phobius details transmembrane" amino acids 15 to 37 (23 residues), see Phobius details amino acids 50 to 69 (20 residues), see Phobius details amino acids 81 to 100 (20 residues), see Phobius details amino acids 106 to 127 (22 residues), see Phobius details amino acids 139 to 163 (25 residues), see Phobius details amino acids 169 to 189 (21 residues), see Phobius details amino acids 224 to 244 (21 residues), see Phobius details amino acids 255 to 273 (19 residues), see Phobius details amino acids 285 to 304 (20 residues), see Phobius details amino acids 315 to 338 (24 residues), see Phobius details amino acids 350 to 370 (21 residues), see Phobius details amino acids 376 to 394 (19 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 14 to 388 (375 residues), 257.9 bits, see alignment E=1.1e-80 PF07690: MFS_1" amino acids 23 to 204 (182 residues), 122.8 bits, see alignment E=1.6e-39 amino acids 223 to 404 (182 residues), 36.3 bits, see alignment E=3.3e-13 PF00083: Sugar_tr" amino acids 49 to 192 (144 residues), 25.7 bits, see alignment E=5.3e-10

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 68% identity to psu:Psesu_2163)

Predicted SEED Role

"MFS transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (417 amino acids)

>ABIE51_RS14645 multidrug effflux MFS transporter (Lysobacter sp. OAE881)
MPTQPATLSIPVRRLALLLGGLAMFGPFSIDTIFPAFPAIGAQFGADKLAMQQTISVYLV
AYALMSIVHGPLSDAIGRRRVILGGLIVFAIASVGCALSKDLTTLLAFRALQGLSSGVGL
IVGRAVIRDVLHGDDAQRLMSQVSMIFGVAPALAPVIGGWILGVAHWPAIFWFLVAFSIV
LIVATWRALPETHPSQARLPLAPKRLLRDYVAIIVNPRFQRLSAAAAFNFAALWVYIASA
PAFVLDILKLSEREFGWFFVPMISGMILGAFVSGRSAGKVSGAKLVSIGFACSAVAMAIN
LGYNLLTDVPKVPWAVLPMMLNAFGIALVFPIVTLAILDMYPRQRGSASSLQAFTGLVLN
AVIAGVLSPLISDHALWLIATAIAFLTIAFGFWRWEARVSRMRNGTEATPTVPGETL