Protein Info for ABIE51_RS14150 in Lysobacter sp. OAE881

Annotation: ATP-dependent Clp protease ATP-binding subunit ClpX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 TIGR00382: ATP-dependent Clp protease, ATP-binding subunit ClpX" amino acids 14 to 415 (402 residues), 677.3 bits, see alignment E=4.3e-208 PF06689: zf-C4_ClpX" amino acids 18 to 54 (37 residues), 72.1 bits, see alignment 1.4e-23 PF00493: MCM" amino acids 72 to 196 (125 residues), 24.7 bits, see alignment E=5.7e-09 PF07724: AAA_2" amino acids 115 to 313 (199 residues), 118.9 bits, see alignment E=1.2e-37 PF07728: AAA_5" amino acids 117 to 194 (78 residues), 27.2 bits, see alignment E=1.7e-09 PF00004: AAA" amino acids 118 to 223 (106 residues), 58.3 bits, see alignment E=5.6e-19 PF10431: ClpB_D2-small" amino acids 320 to 397 (78 residues), 43.2 bits, see alignment E=1.7e-14

Best Hits

Swiss-Prot: 92% identical to CLPX_XANAC: ATP-dependent Clp protease ATP-binding subunit ClpX (clpX) from Xanthomonas axonopodis pv. citri (strain 306)

KEGG orthology group: K03544, ATP-dependent Clp protease ATP-binding subunit ClpX (inferred from 94% identity to psu:Psesu_2043)

MetaCyc: 76% identical to ATP-dependent Clp protease ATP-binding subunit ClpX (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"ATP-dependent Clp protease ATP-binding subunit ClpX" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (429 amino acids)

>ABIE51_RS14150 ATP-dependent Clp protease ATP-binding subunit ClpX (Lysobacter sp. OAE881)
MSDDRQGRSTGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKA
QSARSHLPKPREILEVLDQYVIGQQRAKRTLAVAVYNHYKRIESRQKNDDVELAKSNILL
VGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQ
QGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQ
VDTRNILFVVGGAFAGLDKIIQQRSTEAGGIGFGAKVKSSERKNDIGKLLADVEPEDLIK
FGLIPEFVGRLPVVATLEELDEPALVKILTEPKNAITKQFKKLFEMESVELEFRPDALSA
IARKALKRKTGARGLRTIVESVLLDTMYELPSLENVSKVVVDESVIDHKTEPYLIYQTPP
AAPKVAAAD