Protein Info for ABIE51_RS14120 in Lysobacter sp. OAE881

Annotation: peptidyl-prolyl cis-trans isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 659 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details PF13624: SurA_N_3" amino acids 1 to 46 (46 residues), 37.5 bits, see alignment 5.3e-13 amino acids 68 to 183 (116 residues), 76.7 bits, see alignment E=4.9e-25 PF13623: SurA_N_2" amino acids 68 to 156 (89 residues), 54.5 bits, see alignment E=3.2e-18 PF13145: Rotamase_2" amino acids 268 to 402 (135 residues), 74 bits, see alignment E=4.6e-24 PF13616: Rotamase_3" amino acids 285 to 389 (105 residues), 106.3 bits, see alignment E=3.7e-34 PF00639: Rotamase" amino acids 293 to 389 (97 residues), 99.8 bits, see alignment E=3.6e-32

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 57% identity to xcv:XCV1085)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (659 amino acids)

>ABIE51_RS14120 peptidyl-prolyl cis-trans isomerase (Lysobacter sp. OAE881)
MLQKLRDKTSGWIATVILGLLIIPFAFVGIEQYLGQRTDNSVARIDAPPTWWPTAPAWWP
VSVFWTHEKITSDEFRSRFEQERMQRRAQQGEAFDARAFESVDNKRAILETLIDARVQQI
AAQRNGLVVSDAMVQKAIMDVPGFQVDGKFDYARYKLALASLTPPQSERQFEATVRDDVQ
RSMLAVGVGTSNFVTTAEMDRLVRLMGERRDVSLVLLPPPAPDTAEVSAAEIQKWYDAHT
AQFRAPETVEIEYVEVDASKLPPPAAADEATLRHRYEQEKARFVEAEQRQASHILVRVDE
KADAAAQKAAEEKAKRLAEQAKAPGADFAALARANSDDTGSQVAGGDLGWVAKGMMVAPF
ENALFAMKAGEISAPVKSEFGWHIIQLRDVQTGSQQTFEQVHDQLAREQAEVDRERTVSD
FTSRLVDLTLKNPSSLAPAARDMNLPLQKLGPFARTNAQGIGANPAVQRVAFSEEAIQSG
AISDPIEVAPGHSVLLRVTAHTAEHAQPLAQVRDQVIAAVRADRASKAARKEADALVARV
NKGETLDAIAAEKQLPPPQVVPGVPRGAPVPEAAVSDAIFAVPAPAAGKLSAGHAELSNG
GIALFAVSQVTPGDVATLPAEQRQMLQQQIAQVGGGDDVRALVDSLRKRVKVQVVEQNL