Protein Info for ABIE51_RS13955 in Lysobacter sp. OAE881

Annotation: beta-ketoacyl-ACP synthase III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00747: 3-oxoacyl-[acyl-carrier-protein] synthase III
  • amino acids 6 to 325 (320 residues), 464.7 bits, E=7e-144
• PF00108: Thiolase_N
  • amino acids 38 to 148 (111 residues), 38.3 bits, E=1.6e-13
• PF08545: ACP_syn_III
  • amino acids 110 to 187 (78 residues), 119 bits, E=9.5e-39
• PF08541: ACP_syn_III_C
  • amino acids 237 to 326 (90 residues), 131.4 bits, E=1.7e-42

Best Hits

Swiss-Prot: 82% identical to FABH_XANCP: 3-oxoacyl-[acyl-carrier-protein] synthase 3 (fabH) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K00648, 3-oxoacyl-[acyl-carrier-protein] synthase III [EC: 2.3.1.180] (inferred from 82% identity to xcc:XCC1016)

Predicted SEED Role

"3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180)" (EC 2.3.1.180)

MetaCyc Pathways

• superpathway of fatty acids biosynthesis (E. coli) (48/53 steps found)
• superpathway of fatty acid biosynthesis II (plant) (38/43 steps found)
• superpathway of fatty acid biosynthesis I (E. coli) (14/16 steps found)
• fatty acid biosynthesis initiation (type II) (3/3 steps found)
• superpathway of fatty acid biosynthesis initiation (4/5 steps found)
• streptorubin B biosynthesis (20/34 steps found)

KEGG Metabolic Maps

• Fatty acid biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.180

Use Curated BLAST to search for 2.3.1.180

Protein Sequence (326 amino acids)

>ABIE51_RS13955 beta-ketoacyl-ACP synthase III (Lysobacter sp. OAE881)
MTQQIYSRIAGTGSYLPEKVLTNDDLAKIVDTSDEWIAARTGIRERHIAAEGETTSDLAY
HASVRALEAAGVDATDLDLIVVGTTTPDLIFPSTACLLQHRLGANGCPAFDVNAACTGFV
YALTVADKFIRSGAAKTVLVVGAETLTRMLDWSDRSTCVLFGDGAGAVVLKADTETGILS
THMHADGGKKELLWNPVGVSVGFKPEEHNAGVRVLMTGNEVFKHAVKALDSVVEETLEAN
GLDRHDIDWLIPHQANLRIIEATAKRLDMPMDRVVVTVDKHGNTSSGSVPLALDEAVRSG
KVQRGQLVLLEAFGGGFTWGSALLRY