Protein Info for ABIE51_RS13910 in Lysobacter sp. OAE881

Annotation: DNA polymerase III subunit delta'

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13177: DNA_pol3_delta2
  • amino acids 12 to 177 (166 residues), 144.7 bits, E=1.4e-46
• TIGR00678: DNA polymerase III, delta' subunit
  • amino acids 17 to 211 (195 residues), 193.3 bits, E=1.6e-61

Best Hits

KEGG orthology group: K02341, DNA polymerase III subunit delta' [EC: 2.7.7.7] (inferred from 67% identity to xcv:XCV1151)

Predicted SEED Role

"DNA polymerase III delta prime subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

• Purine metabolism
• Pyrimidine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Protein Sequence (326 amino acids)

>ABIE51_RS13910 DNA polymerase III subunit delta' (Lysobacter sp. OAE881)
MSANVANFAPWQQRVYDQAVAALDAGRLAHGLLFCGPAKLGKRAVAERLARRVLCQQPVA
GGEPCGKCRSCHLIDSGTHPDYHVVSFVPNKEGTRLRTEIVIEQIRELSEKLSLTPQYGG
AQVAILDPAEAINNAAGNALLKTLEEPVPGRYLWLVSAHPARLSATIRSRCQRYEFKLPP
HDEALAWLRGNGHADAVAREALDAARGHPGLAQEWIENDGLKLRRDVAADLAKLGRGDAG
AVEIAQRWVGDEQAALRLRHAADLALAEAAGLTDPMRTRSLAAWFDQANRTRDLLRTTVR
ADLAVTELLLAWRGANGAQASGGSRR