Protein Info for ABIE51_RS13495 in Lysobacter sp. OAE881

Annotation: TRZ/ATZ family hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 PF01979: Amidohydro_1" amino acids 67 to 414 (348 residues), 232.4 bits, see alignment E=9.6e-73 PF07969: Amidohydro_3" amino acids 186 to 414 (229 residues), 61.6 bits, see alignment E=1e-20

Best Hits

Swiss-Prot: 46% identical to MTAD_TERTT: 5-methylthioadenosine/S-adenosylhomocysteine deaminase (mtaD) from Teredinibacter turnerae (strain ATCC 39867 / T7901)

KEGG orthology group: None (inferred from 81% identity to psu:Psesu_1209)

Predicted SEED Role

"S-adenosylhomocysteine deaminase (EC 3.5.4.28); Methylthioadenosine deaminase" (EC 3.5.4.28)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.28

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (447 amino acids)

>ABIE51_RS13495 TRZ/ATZ family hydrolase (Lysobacter sp. OAE881)
MTHDRTPEACDLLIEAGWVVPVVPHGVVLEDHAVAVRDGEIVAVLPTREARARFDAAETV
SRPDAALIPGLVNAHTHNPMTLLRGIADDLPLMEWLQGHIWPVEGAVMGPEFIEDGIALA
IAEMLRGGTTCANENYFFPDVQAAVYKQHGFRARVGLPVIDFPTAWAKTSEEYFERAGEV
HDQWRDDPLVATTFAPHAPYTVSDENFERIRMLSDQLDIPVHLHTHETAHEVSESHAKLG
QRPIARLDRLGLINDRLIAVHMTQLTDAEIALCAQRGVSVVHCPESNLKLASGFCPVGKL
VKAGVNVAIGTDGCASNNDLDMFGETRTAALLAKAVAEDASAFDAATALHAATLGGARSL
GFEAKIGSIEPGKQADLVCVDLGQIETQPLHHVVSQLIYATGRHHVSDVWIAGRAKLRER
MLVDMDAAALVANARQWRERIAAIRLT