Protein Info for ABIE51_RS13135 in Lysobacter sp. OAE881

Annotation: S8 family serine peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1066 PF00082: Peptidase_S8" amino acids 211 to 505 (295 residues), 157.3 bits, see alignment E=8.2e-50 TIGR02601: autotransporter-associated beta strand repeat" amino acids 545 to 576 (32 residues), 28.4 bits, see alignment (E = 5.5e-11) PF12951: PATR" amino acids 546 to 575 (30 residues), 26.3 bits, see alignment (E = 9.3e-10) PF03797: Autotransporter" amino acids 801 to 1046 (246 residues), 108.8 bits, see alignment E=6.4e-35

Best Hits

Predicted SEED Role

"Outer membrane stress sensor protease DegS" in subsystem Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1066 amino acids)

>ABIE51_RS13135 S8 family serine peptidase (Lysobacter sp. OAE881)
MIDECEHTGRRAGVDEFAKRLAVGFAFRCLPRAPAHRHAPPHAPAPVAGTTWAEQRFDDG
PVVATQRSGVDGVHRVHRCARNVAPDAVSVTGSCRLIVDDPHWVDTRFAIAGERCDFIQM
GSVMHYRHKELVTAMRSVLLCSGLMGLAACGGGGGGGNVRETPPLYAPTTPTTPPPPTNP
TPPVVSTPSPAYSQHISLTAADFAHRAGITGKGVRIGVVDSGVMRNHPALAPRVVANLNY
VASPPNNLAVDDVAGHGTAVSQIAAGTPFGAWPGGIAPGAEIVSARILYDEDPKDDGSGQ
GNEVDGAIGLKAIHQDLINRGVRVMNNSWGGLYWTNPAATGPIADEYRPFINSNNGLVVF
ATGNEGGANPSSMAALPSQVGLNGTLPAADLERGWLAVTAVNPNNTQQLDVDTKGVVYAN
ACGVAMRYCLAAPGTVAVTGTTDGPTSPTYWRWSGTSLAAPQVSGAAALVWQAFPYFSND
MVRQTLLGGATDLGQPGPDATFGYGLLNIAWAMRGPTKFDWGDANVTVPDGTSSTWANPI
SGAGGLIKQGAGKLILSERGSYAGRTQVLGGELQVSSEITSPVTIGPQGTLSGYARFGAV
ENSGTFRVDNVARVVGDYQQTASGRLSILLGAWLYVEGTATLGGDLHVLGARSGYVASSY
TPFLSAPSIVGSFASLSSAPGVFLDATIKYGPTDVWLDVRRLDVTATAQSMGLTATSVGS
AQRVEGTFDAIDQGAAVPDNVLTGAGAIQGSPTAAAAEQTLSSLSGELHVADTAFAMMAI
EGNRRALESRIDALQDAPLGGAWFDDLDSQRALARFDMQADGWMAGQDRRVGALTVGAAL
AQTEGYAHHEQRFDREHNRQLEAQFYASYDLGQGYLLGSVAVGRMQRWTRRDVLLGADAF
RLGTDYAQRYASVGMQAGLPMNVGEGRITPYVGVQNLQLERDGFSEAGAVGFGLSTDASS
MRVSQALLGARYATQWNVGWTQWDLQARAEWQRLLSQSGGDIQARFTALEVWSPILGGAL
DRDVGVLGFGIGTWLRYNSRLSLDVDARSDHGETWTQAMLNWTMAF