Protein Info for ABIE51_RS12405 in Lysobacter sp. OAE881

Annotation: very short patch repair endonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 145 TIGR00632: DNA mismatch endonuclease Vsr" amino acids 1 to 118 (118 residues), 139.5 bits, see alignment E=3e-45 PF03852: Vsr" amino acids 2 to 75 (74 residues), 102.8 bits, see alignment E=3.7e-34

Best Hits

Swiss-Prot: 48% identical to VSX2_XANOR: XorII very short patch repair endonuclease (vsr) from Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)

KEGG orthology group: K07458, DNA mismatch endonuclease, patch repair protein [EC: 3.1.-.-] (inferred from 63% identity to psu:Psesu_2195)

Predicted SEED Role

"Very-short-patch mismatch repair endonuclease (G-T specific)" in subsystem DNA repair, bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (145 amino acids)

>ABIE51_RS12405 very short patch repair endonuclease (Lysobacter sp. OAE881)
MADTLTPQARSERMGRIRSKDTRPELLVRRAVWRAGFRYRLHVKGMPGRPDLVFPRLRTV
VFVHGCYWHAHTCQKGRIPGANRQFWHDKFMANQSRDERDRAELRRLGWRVIVVWECALA
SAARRESTLRGVLDKLREVPPGSSP