Protein Info for ABIE51_RS12265 in Lysobacter sp. OAE881

Annotation: DEAD/DEAH box helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 702 PF00270: DEAD" amino acids 37 to 202 (166 residues), 173.2 bits, see alignment E=7.8e-55 PF04851: ResIII" amino acids 53 to 197 (145 residues), 28.9 bits, see alignment E=2e-10 PF00271: Helicase_C" amino acids 239 to 347 (109 residues), 103.6 bits, see alignment E=1.5e-33 PF03880: DbpA" amino acids 583 to 653 (71 residues), 87.7 bits, see alignment E=8.5e-29

Best Hits

Predicted SEED Role

"DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13)" (EC 3.6.4.13)

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (702 amino acids)

>ABIE51_RS12265 DEAD/DEAH box helicase (Lysobacter sp. OAE881)
MSAEPSSNDAPSLKFTDLALPEPLLKALSDVGYESPSPIQAATIPPLLEGRDVLGQAQTG
TGKTAAFALPILAQIQPGRQKPQALVLAPTRELAIQVAEAFQKYAHHLPGFHVLPIYGGQ
SYYPQLQALKRGVQVVVGTPGRVIDHLERGSLDLSELRCLVLDEADEMLRMGFIDDVEAV
LKKTPETRQVALFSATMPPPIRRIAQTYLKDPVEISIKAKTTTAANIRQRYWAVSGVHKL
DAITRILEAEPFDAMIVFARTKQATEELADKLAARGIAAAAINGDVQQAQREKTIQNLKD
GKIDVLVATDVAARGLDVERISHVLNFDIPYDTESYVHRIGRTGRAGRKGEAILFVTPRE
RGMLRAIERATRQPIEPMALPTIETVNEQRVNRFLGRITGALDSDDLAQFRDLVERYERE
QNVPAVEIAAALAKLLQGDMPLLLDVTAEKLRPHAQVGFEQRGPREQGRDSRGRDRDSRF
ERDSGPRAPRESRHESRHERGDRSERPQRTETPYAPTERYERPAIERPQFEPRSERPQNE
RASFNAAESMFDDEASTPRHEHREPREHREPRETRAPEVGMETFRIEVGHQHGVKPGNIV
GAIANEAELESRYIGRIDIRDDHSLIDLPEGMPREVMDHLKRVRVAGQQLRISRPGEGGH
GGQRPHGRHERGGFDDDRRPPRGPRPQGAGPRKPGGFRPKPR