Protein Info for ABIE51_RS11940 in Lysobacter sp. OAE881

Annotation: methanethiol S-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 transmembrane" amino acids 7 to 31 (25 residues), see Phobius details amino acids 45 to 66 (22 residues), see Phobius details amino acids 86 to 103 (18 residues), see Phobius details amino acids 122 to 146 (25 residues), see Phobius details amino acids 177 to 211 (35 residues), see Phobius details PF07298: NnrU" amino acids 55 to 189 (135 residues), 26.7 bits, see alignment E=4.1e-10 PF04140: ICMT" amino acids 167 to 218 (52 residues), 24.9 bits, see alignment E=2.3e-09

Best Hits

Swiss-Prot: 61% identical to MDDA_CYAA5: Methanethiol S-methyltransferase (mddA) from Cyanothece sp. (strain ATCC 51142)

KEGG orthology group: None (inferred from 67% identity to cyp:PCC8801_0005)

Predicted SEED Role

"putative conserved integral membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>ABIE51_RS11940 methanethiol S-methyltransferase (Lysobacter sp. OAE881)
MKRWLILLYGVACYAVFFATFLYAIGFVGGFGVPKSMDSPRDTSLPIALAINLGLLALFA
LQHSVMARPAFKRAWTRVIPESAERSTYTLLSSVALILLFWQWRPLGGIVWHVENEVGRV
LLYAAFAFGWVLVLVSTFLINHFDLFGLRQVWLQFRGRPYRPLPFKTPGPYRIVRHPLYV
GWFFAFWATPTMTVTHLVFALMTTAYILIAIRLEERDLLDALPEYAQYRRDVPMLVPRTS
RASRGVATRHAGTTAQ