Protein Info for ABIE51_RS11810 in Lysobacter sp. OAE881

Annotation: response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 215 PF00072: Response_reg" amino acids 5 to 117 (113 residues), 90.4 bits, see alignment E=8.8e-30 PF00196: GerE" amino acids 147 to 203 (57 residues), 53.8 bits, see alignment E=1.2e-18

Best Hits

Swiss-Prot: 48% identical to GACA_PSEVI: Response regulator GacA (gacA) from Pseudomonas viridiflava

KEGG orthology group: None (inferred from 74% identity to xac:XAC2110)

Predicted SEED Role

"BarA-associated response regulator UvrY (= GacA = SirA)" in subsystem Pseudomonas quinolone signal PQS or Quorum sensing regulation in Pseudomonas or Type III secretion system orphans

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (215 amino acids)

>ABIE51_RS11810 response regulator (Lysobacter sp. OAE881)
MEIRVFIIDDHALVRTGLNLILSGENDIEVVGDAESGEEALPLIRKLKPDVVLCDLHLPG
LSGLEVTERIVKSEQAARVIIVSVLQDGPMPKRLLEAGASGYVGKGGDAAELLRAIREVA
RGKRFLANGIAQNLALAGIDGGASPFDSLSPREMEIALMLIQGLRQDVIAKRLSLSAKTV
NTHKARLFEKLDIGDSIALARLASRYGIMDPTRAI