Protein Info for ABIE51_RS11805 in Lysobacter sp. OAE881

Annotation: ribonuclease E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1075 TIGR00757: ribonuclease, Rne/Rng family" amino acids 13 to 423 (411 residues), 535.3 bits, see alignment E=5.3e-165 PF00575: S1" amino acids 36 to 116 (81 residues), 34 bits, see alignment 4.8e-12 PF10150: RNase_E_G" amino acids 120 to 389 (270 residues), 342.7 bits, see alignment E=2.4e-106 PF20833: RNase_E_G_Thio" amino acids 401 to 486 (86 residues), 110.7 bits, see alignment E=4.7e-36

Best Hits

KEGG orthology group: K08300, ribonuclease E [EC: 3.1.26.12] (inferred from 68% identity to psu:Psesu_1711)

Predicted SEED Role

"Ribonuclease E (EC 3.1.26.12)" in subsystem RNA processing and degradation, bacterial or Ribosome biogenesis bacterial (EC 3.1.26.12)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1075 amino acids)

>ABIE51_RS11805 ribonuclease E (Lysobacter sp. OAE881)
MKRMLINATQAEELRVAIVDGQTLYDIDIEQPAKEQKKSNIYKGRITRLEPSLEAAFVEY
GAERHGFLPLKEISRDYFQAGVDHNKAGLRELLREGQEIVVQVDKEERGNKGAALTTFIS
LAGRYMVLMPNSPTAGGVSRRIEGEDRAELKRAMDALNIPDDMGVIIRTAGVGRDAEELQ
WDLDYLLQVWKSVAEAALSKPGPFLIYQESRLIIRALRDYMRPDIGEILVDTPEMYAEAR
DFVEQVMPHNLRKLKHYTDDTPLFNRFQIESQIENAYEREVRLPSGGALVIDQTEALTAI
DVNSARATKGGDIEETAFNTNLEAAEEVARQMRLRDLGGLVVIDFIDMSSNKHQREVENR
LAHALKQDRARVQIGRISRFGLLELSRQRLRPSLGESSQLVCPRCEGHGRMRSVESLSLS
ILRLAEEHAMKENTGQVLVQAPTEIANYLLNEKRRALSEIEKRHDAPIVIVADEQLHTPH
YEVTRIRENELGEESNKPSYQRGTPRKLPTHSLTKAHLNIPAAPAVTNVKPAQPAPLREP
REQQVAAPAPAPAPAPVAAPTHSIGVVERILRFFRGTSSPIAVEPTPAARPQDNRGGRNE
RGDRNDKRRDGRNGKQGRDGRRDDQPRREEQRRDEPRRDERRDEQRREKQPQQAQQQKQP
KQQQQQQQQQPKQQQQQQQKQPKQQQSQQQAQAQQSQVEDRVQQPAAEARPPRNENRPAP
AKAEVKPDVVKAETPATTAADVALVAPAVVAAAVTASETTEAATPAVVQTGEAVAHADAT
QGEGAGEGGSRRRRGRRGGRRRRRGGGDAAAGTDEAQLHDEHDDASLLDDEDDAHEANAA
EGTAPAPVAQRSQPEFDFDDEPATTSPTVPSNVTHSPAIPAPVATPAQAAVATVAAVAVA
TGETAAPKADQPQVAAPPEPQAPAEPAVVVEQPVVVPEPVPEPEKVEEPAVIDPAPVVPA
EDARPQKQAEAETTDSRPQASTPSAAPLANGDVPRTAGLFDSLPHDTRAPAAETAPVPAP
VEASVAGESQADEAAPDTVAADADEAAPSPAEAAAEHVHAAAQGEGERKQESGHV