Protein Info for ABIE51_RS11455 in Lysobacter sp. OAE881

Annotation: DNA translocase FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 786 transmembrane" amino acids 30 to 49 (20 residues), see Phobius details amino acids 80 to 106 (27 residues), see Phobius details amino acids 119 to 137 (19 residues), see Phobius details amino acids 173 to 195 (23 residues), see Phobius details PF13491: FtsK_4TM" amino acids 24 to 200 (177 residues), 154.6 bits, see alignment E=4.3e-49 PF17854: FtsK_alpha" amino acids 286 to 386 (101 residues), 105.3 bits, see alignment E=3.5e-34 PF01580: FtsK_SpoIIIE" amino acids 394 to 607 (214 residues), 252.2 bits, see alignment E=8.1e-79 PF09397: FtsK_gamma" amino acids 721 to 781 (61 residues), 92.9 bits, see alignment 1.6e-30

Best Hits

Swiss-Prot: 82% identical to FTSK_XANCP: DNA translocase FtsK (ftsK) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 84% identity to xal:XALc_1450)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (786 amino acids)

>ABIE51_RS11455 DNA translocase FtsK (Lysobacter sp. OAE881)
MAQASAASRKKLKAEKLPPSPRKQRLVRDIALILIAPLLLYLLASLVTFSPQDPGWSHSG
SVTAPLHNVGGRVGAWTADVLLYLCGYVAFLLPIMLGAIAWIALFGMDTDGDGEADFGPA
LRLVGIVGFLVAATGLLELRVGTAEAFSARAGGILGQLVGKSLYSGFGPVGGNLFLLALL
LVSVTLATGLSWFAVMDKIGQWVLAFGPTLSTLFRKGEKQATEWQQTRAMREEREEARKV
DTELRAKRAPVKIEPPPPAAAVVEKSERAKRETQIPLFHTGDGTGIPPLALLDDPKPQPK
GYDEQTLETLSRQIEFKLKDFRIDAQVVGAYPGPVITRFEIEPAPGVKVSQISTLDKDIA
RGLSVKSVRVVDVIPGKSVIGLETPNTSREMIFLSELLRSKEYDKSTSPLTLALGKDIAG
RPTVADLARMPHLLVAGTTGSGKSVAVNAMVLSLLYKASAKDLRMLMIDPKMLELSVYQG
IPHLLAPVVTDMKEAANGLRWCVAEMERRYKLMSSVGVRNLAGFNKKVKDAIDAGQPMMD
PLFKPNAELGETPRPLETLPFIVIFIDEFADMMMIVGKKVEELIARLAQKARAAGIHLIL
ATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQSGAETLLGHGDMLYLPPGTAMP
ERVHGAFVSDEEVHRVVEHLKQIGGGPDYIEGVLDEVQTMGDGVVVGATGLPETGGGGGD
ESDPLYDEAVRIVTETRRASISGVQRRLKIGYNRAARLIEAMEAAGVVTPPEHNGDRSVL
APPPPK