Protein Info for ABIE51_RS11230 in Lysobacter sp. OAE881

Annotation: serine hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 534 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00144: Beta-lactamase" amino acids 33 to 374 (342 residues), 244.6 bits, see alignment E=1.6e-76 PF11954: DUF3471" amino acids 420 to 525 (106 residues), 98.3 bits, see alignment E=3.2e-32

Best Hits

KEGG orthology group: None (inferred from 70% identity to xal:XALc_2047)

Predicted SEED Role

"Beta-lactamase (EC 3.5.2.6)" in subsystem Beta-lactamase or Tn552 (EC 3.5.2.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.6

Use Curated BLAST to search for 3.5.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (534 amino acids)

>ABIE51_RS11230 serine hydrolase (Lysobacter sp. OAE881)
MHRRTVSAALALLIATGAAHASDTALPPQLQNFDAYVEGVRKQFDVPGIAVAVVKDGQVV
LERGFGVREMNKPAQVDANTLFAIASNTKAFTAASLSILADEGKLSLDDRVIDHLPWFRM
SDAYVTQEMRVRDLLAHRSGLGLGAGDLLYWPGTDYTTEDVARRLKDVPLTGSFRGEYAY
DNILYGVAQLVIEQASGQSYAQFLQQRIFAPLGMRDTRFNSDALRPRDNVATGHAKADFK
DLQPAPRMTWHNVSGAGGIYSSVHDMSRWMNMQLAGGTFTDAKGTQQRLFSEERQQEMWS
VITPIPIPKPAVPELEAAKPNFLGYGEGWTLSDYRGRKLVSHTGGWPGMVSRVTLVPQQK
LGVIVLTNAEVGGAFNAVTMRVLDAFLDAPRTDWTAAYAAALAKSKDKSDEDWRKHVEAR
VANAPPSRPLSAYARTYRDPWYGDIVVEQAKDGLVMRFSRTPDLVGKMEPWQHDTFVVRW
NERWLNADAFVTFSLDADGKVREGRMEAISPLTDFSFDFQDLRLKPVEQEKPKS