Protein Info for ABIE51_RS10010 in Lysobacter sp. OAE881

Annotation: potassium-transporting ATPase subunit KdpC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 transmembrane" amino acids 30 to 50 (21 residues), see Phobius details TIGR00681: K+-transporting ATPase, C subunit" amino acids 25 to 206 (182 residues), 175.7 bits, see alignment E=5.1e-56 PF02669: KdpC" amino acids 27 to 205 (179 residues), 220.2 bits, see alignment E=9.6e-70

Best Hits

Swiss-Prot: 67% identical to KDPC_XANOM: Potassium-transporting ATPase KdpC subunit (kdpC) from Xanthomonas oryzae pv. oryzae (strain MAFF 311018)

KEGG orthology group: K01548, K+-transporting ATPase ATPase C chain [EC: 3.6.3.12] (inferred from 62% identity to gpb:HDN1F_36020)

MetaCyc: 45% identical to K+ transporting P-type ATPase subunit KdpC (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-2 [EC: 7.2.2.6]

Predicted SEED Role

"Potassium-transporting ATPase C chain (EC 3.6.3.12) (TC 3.A.3.7.1)" in subsystem Potassium homeostasis (EC 3.6.3.12, TC 3.A.3.7.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.12

Use Curated BLAST to search for 3.6.3.12 or 7.2.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (208 amino acids)

>ABIE51_RS10010 potassium-transporting ATPase subunit KdpC (Lysobacter sp. OAE881)
MSTTASSITLNASARGDHTLDDRTTLRPSLAFAAVILLGFGFLYSLAGTGIGRVLFPYQA
TGSLVVVDGTPRGSALVAQPFADARYFQPRPSAGNYDPMAAAGSNLARGNPDLRERMAAL
RQQVAKRYGISPDEVPAELVTMSGSGMDPHLSPAGARVQIARVAKARGLNEADVAALVAE
HTEPATFGALGEPRVNVLELNLALDAKR