Protein Info for ABIE51_RS09790 in Lysobacter sp. OAE881

Annotation: ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 transmembrane" amino acids 39 to 59 (21 residues), see Phobius details amino acids 65 to 85 (21 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details amino acids 119 to 136 (18 residues), see Phobius details amino acids 143 to 164 (22 residues), see Phobius details amino acids 176 to 196 (21 residues), see Phobius details PF02518: HATPase_c" amino acids 337 to 437 (101 residues), 68.8 bits, see alignment E=2.7e-23

Best Hits

KEGG orthology group: K15011, two-component system, sensor histidine kinase RegB [EC: 2.7.13.3] (inferred from 60% identity to vap:Vapar_4051)

Predicted SEED Role

"Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3, 2.7.3.-

Use Curated BLAST to search for 2.7.13.3 or 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (454 amino acids)

>ABIE51_RS09790 ATP-binding protein (Lysobacter sp. OAE881)
MASRTIQDAVAADAESRLPALTRWRGSAGLRNMQQLIELRWIAVIGQVATIIVVHYGLGI
GLPLRPMFTVLAALALFNVVSQLWWRRREHASSNALMVSLLVDVASLTIQLYLSGGITNP
FVFLYLLQVVLGTVVLRSPWSWVIAAAAALCVTGLTLVRTPIVLAVEPARGLGDHYVQGL
LICFLLIAALLVVFLTRIGRILRERDARLAELRQRAAEEEHIVRMGLLASGAAHELGTPL
STLSVILGDWQHLPTIASEGELHRDVVEMQQQVARCKSIVTNILLAAGGPRAEAPIEVSL
HAMLDGLAEEWRRARNPSQFTYTNRCHLDPRIVSDAGLRQMVFNVLDNALEASPGWVALD
AHCDGEALIIDVSDAGPGFSGEILQRLGSPYNTSKGRPGGGLGLFLSVNVARTLGGSLRA
KNRPQGGAVVTMTLPLSALAIEDESDEEGDDAED